Medical geneticsMedical genetics is the branch of medicine that involves the diagnosis and management of hereditary disorders. Medical genetics differs from human genetics in that human genetics is a field of scientific research that may or may not apply to medicine, while medical genetics refers to the application of genetics to medical care. For example, research on the causes and inheritance of genetic disorders would be considered within both human genetics and medical genetics, while the diagnosis, management, and counselling people with genetic disorders would be considered part of medical genetics.
World populationIn demographics, the world population is the total number of humans currently living. It was estimated by the United Nations to have exceeded eight billion in mid-November 2022. It took over 200,000 years of human prehistory and history for the human population to reach one billion and only 219 years more to reach 8 billion. The human population has experienced continuous growth following the Great Famine of 1315–1317 and the end of the Black Death in 1350, when it was nearly 370,000,000.
Genetic distanceGenetic distance is a measure of the genetic divergence between species or between populations within a species, whether the distance measures time from common ancestor or degree of differentiation. Populations with many similar alleles have small genetic distances. This indicates that they are closely related and have a recent common ancestor. Genetic distance is useful for reconstructing the history of populations, such as the multiple human expansions out of Africa. It is also used for understanding the origin of biodiversity.
Evolutionary landscapeAn evolutionary landscape is a metaphor or a construct used to think about and visualize the processes of evolution (e.g. natural selection and genetic drift) acting on a biological entity (e.g. a gene, protein, population, or species). This entity can be viewed as searching or moving through a search space. For example, the search space of a gene would be all possible nucleotide sequences. The search space is only part of an evolutionary landscape. The final component is the "y-axis", which is usually fitness.
Population declinePopulation decline, also known as depopulation, is a reduction in a human population size. Over the long term, stretching from prehistory to the present, Earth's total human population has continued to grow; however, current projections suggest that this long-term trend of steady population growth may be coming to an end. Until the beginning of the Industrial Revolution, the global population grew very slowly, at about 0.04% per year. After about 1800, the growth rate accelerated to a peak of 2.
Genetic driftGenetic drift, also known as random genetic drift, allelic drift or the Wright effect, is the change in the frequency of an existing gene variant (allele) in a population due to random chance. Genetic drift may cause gene variants to disappear completely and thereby reduce genetic variation. It can also cause initially rare alleles to become much more frequent and even fixed. When few copies of an allele exist, the effect of genetic drift is more notable, and when many copies exist, the effect is less notable.
Genetic testingGenetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or through biochemical analysis to measure specific protein output. In a medical setting, genetic testing can be used to diagnose or rule out suspected genetic disorders, predict risks for specific conditions, or gain information that can be used to customize medical treatments based on an individual's genetic makeup.
Projections of population growthPopulation projections are attempts to show how the human population statistics might change in the future. These projections are an important input to forecasts of the population's impact on this planet and humanity's future well-being. Models of population growth take trends in human development and apply projections into the future. These models use trend-based-assumptions about how populations will respond to economic, social and technological forces to understand how they will affect fertility and mortality, and thus population growth.
Human geneticsHuman genetics is the study of inheritance as it occurs in human beings. Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling. Genes are the common factor of the qualities of most human-inherited traits. Study of human genetics can answer questions about human nature, can help understand diseases and the development of effective treatment and help us to understand the genetics of human life.
Scientific literatureScientific literature comprises academic papers that report original empirical and theoretical work in the natural and social sciences. Within a field of research, relevant papers are often referred to as "the literature". Academic publishing is the process of contributing the results of one's research into the literature, which often requires a peer-review process. Original scientific research published for the first time in scientific journals is called the primary literature.
