Fundamental bounds on the precision of iSCAT, COBRI and dark-field microscopy for 3D localization and mass photometry
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In this thesis new imaging approaches for optical microscopy are proposed and studied. They are based on the use of dynamic structured illumination in combination with a demodulation detection concept employing CMOS image detectors. Two particular implemen ...
The image of a sub-resolution nano-particle in fluorescence microscopy corresponds to a slice of the 3D point spread function (PSF). This slice relates to the out-of-focus distance of the nano-particle. In this paper, we investigate to which extent it is p ...
A new class of molecules for the preparation of self-assembling biomaterials were synthesized. These molecules consist of a cholesteryl-moiety attached via an oligo(ethylene oxide) or oligo(L-lactic acid) segment to a biologically relevant headgroup. The o ...
A non-parametric method of distribution estimation for univariate data is presented. The idea is to adapt the smoothing spline procedure used in regression to the estimation of distributions via a scatterplot smoothing of theempirical distribution function ...
