Publication

Validating atlas-based lesion disconnectomics in multiple sclerosis: A retrospective multi-centric study

Related publications (44)

Exploring dynamic functional connectivity by incorporating prior knowledge of brain structure

The synchronized firing of distant neuronal populations gives rise to a wide array of functional brain networks that underlie human brain function. Given the enormous perception, learning, and cognition potential of the human brain, it is not surprising th ...

EPFL2020

Towards quantitative brain connectomics: microstructure informed tractography via convex optimization

Muhamed Barakovic

Tractography is the only non-invasive technique which is used to reconstruct the white mat- ter structural connectivity of the human brain. It relies on a specific Magnetic Resonance Imaging (MRI) acquisition, called diffusion MRI, which is sensitive to th ...

EPFL2019

Is it feasible to directly access the bundle’s specific myelin content, instead of averaging? A study with Microstructure Informed Tractography

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Marco Pizzolato, Alessandro Daducci

Diffusion MRI connectometry is a widely used tool to investigate features of structural connectomes that reflect differences in white matter tracks integrity. It consists in averaging microstructural tissues properties (obtained from any voxel-wise map) al ...

2019

On the intrahemispheric connectivity of the monkey: a diffusion tractography and tract tracing analysis

Gabriel Girard, Maxime Descoteaux, Giorgio Innocenti

In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingulate and parietal areas of the monkey. In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingul ...

International Society for Magnetic Resonance in Medicine2019

Limits to anatomical accuracy of diffusion tractography using modern approaches

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, David Paul Roger Romascano, Elda Fischi Gomez, Marco Pizzolato, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux, Gaëtan Olivier D Rensonnet, Alice Philippa Bates, Tim Bjørn Dyrby, Chao Huang

Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the brain, with a range of applications in both clinical and basic neuroscience. Despite widespread use, tractography has well-known pitfalls that limits the anatomical ...

2018

Fiber orientation distribution function from non-negative sparse recovery with quantitative analysis of local fiber orientations and tractography using DW-MRI datasets

Gabriel Girard

Diffusion weighted MRI (DW-MRI) is the unique non-invasive imaging modality capable of estimating in vivo the structure of the white matter. In this paper, we propose, evaluate and validate a new DW-MRI method to model and recover high quality tractogram e ...

2018

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Many closed-form analytical models have been proposed to relate the diffusion-weighted magnetic resonance imaging (DW-MRI) signal to microstructural features of white matter tissues. These models generally make assumptions about the tissue and the diffusio ...

2018

Exploring the role of white matter connectivity in cortex maturation

Alessandra Griffa, Patric Hagmann, Petra Susan Hüppi

The maturation of the cortical gray matter (GM) and white matter (WM) are described as sequential processes following multiple, but distinct rules. However, neither the mechanisms driving brain maturation processes, nor the relationship between GM and WM m ...

2017

Surface-enhanced tractography (SET)

Gabriel Girard, Alessandro Daducci, Maxime Descoteaux

In this work, we exploit the T1 weighted image in conjunction with cortical surface boundary to improve the precision of tractography under the cortex. We show that utilizing the cortical interface and a surface flow, to model the superficial white matter ...

Elsevier2017

The challenge of mapping the human connectome based on diffusion tractography

Jean-Philippe Thiran, Gabriel Girard, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux, Alia Lemkaddem, Anna Auria Rasclosa, Ying-Chia Lin, Tim Bjørn Dyrby

Tractography based on non-invasive diffusion imaging is central to the study of human brain connectivity. To date, the approach has not been systematically validated in ground truth studies. Based on a simulated human brain data set with ground truth tract ...

Nature Publishing Group2017

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