Publication

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

Related publications (61)

Identifying Adverse Effects of HIV Drug Treatment and Associated Sentiments Using Twitter

Background: Social media platforms are increasingly seen as a source of data on a wide range of health issues. Twitter is of particular interest for public health surveillance because of its public nature. However, the very public nature of social media pl ...

2015

A Systems Approach to Identify Genetic and Environmental Regulators of Metabolism

Evan Graehl Williams

For more than a century, it has been recognized that our genetic inheritance and our environment interact to shape who we are and how we act (nature vs. nurture), and the study of genetics has allowed us to explain why traits can vary dramatically betwee ...

EPFL2014

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

Jacques Fellay, Amalio Telenti

Natural progression of HIV-1 infection depends on genetic variation in the human major histocompatibility complex (MHC) class I locus, and the CD8(+) T cell response is thought to be a primary mechanism of this effect. However, polymorphism within the MHC ...

Public Library of Science2014

Targeting HIV-related Medication Side Effects and Sentiment Using Twitter Data

Marcel Salathé

We present a descriptive analysis of Twitter data. Our study focuses on extracting the main side effects associated with HIV treatments. The crux of our work was the identification of personal tweets referring to HIV. We summarize our results in an infogra ...

2014

Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons

Jacques Fellay, Amalio Telenti, Xuan Li

Background. Persons infected with human immunodeficiency virus (HIV) have increased rates of coronary artery disease (CAD). The relative contribution of genetic background, HIV-related factors, antiretroviral medications, and traditional risk factors to CA ...

Oxford University Press2013

Seismic assessment of existing buildings, Approach based on the risk used in Switzerland

Pierino Lestuzzi

Chapter 6. ...

John Wiley & Sons, Inc.2013

Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

Istvan Bartha

Background: Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential ro ...

Biomed Central Ltd2013

Polyvalent Side Chain Peptide-Synthetic Polymer Conjugates as HIV-1 Entry Inhibitors

Harm-Anton Klok, Maarten Danial

This report describes the synthesis and properties of a series of polyvalent side chain peptide synthetic polymer conjugates designed to block the CD4 binding site on gp120 and inhibit HIV-1 entry into a host cell. The peptide sequences in the conjugates a ...

2012

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

Didier Trono

HIV infection can persist in spite of efficacious antiretroviral therapies. Although incomplete inhibition of viral replication may contribute to this phenomenon, this is largely due to the early establishment of a stable reservoir of latently infected cel ...

American Association for the Advancement of Science2010

A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro

Jacques Fellay, Wei Huang

A single-nucleotide polymorphism (rs2395029) in the HCP5 gene associated with HLA-B*5701 is correlated with lower HIV-1 viral set point. The two allelic forms of coding region were ectopically expressed in TZM-bl cells for an effect on HIV-1 replication. N ...

2010

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