A 0.4 nJ Excitation Energy Bridge-to-Digital Converter for Implantable Pulmonary Artery Pressure Monitoring
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In the developing heart, a subset of endothelial cells (ECs) undergo a process of endothelial to mesenchymal transformation (EMT) that leads to the remodeling of the cardiac cushions and the formation of the cardiac valves. Understanding how microenvironme ...
We describe a device made of artificial muscle for the treatment of end-stage heart failure as an alternative to current heart assist devices. The key component is a matrix of nitinol wires and aramidic fibers called Biometal muscle (BM). When heated elect ...
Mechanical circulatory support, in particular ventricular assist devices (VAD), has been recently proposed as an alternative to transplantation in the treatment of terminal heart failure in the context of the lack of donors and raising number of patients o ...
Motivated by the growing wealth of biological data and the increasing pathophysiological knowledge at different scales, spectacular progress have been made in comprehensive modeling to understand the complex nature of biological organs, such as the heart. ...
The electronic miniaturization and the computer evolution (microprocessor, transputer) have contributed to the use of electric drives in a lot of applications. Because of its flexibility, the electric drive becomes an essential element to work out new conc ...
The mechanical interactions between heart contraction and perfusion of the heart are difficult to study in humans because of the restrictions in inducing changes in hemodynamic and cardiac mechanics parameters during catheterization. We hypothesize that th ...
The vitamin D(3) and nicotine (VDN) model is a model of isolated systolic hypertension (ISH) due to arterial calcification raising arterial stiffness and vascular impedance similar to an aged and stiffened arterial tree. We therefore analyzed the impact of ...
The pulmonary venous systolic flow wave has been attributed both to left heart phenomena, such as left atrial relaxation and descent of the mitral annulus, and to propagation of the pulmonary artery pressure pulse through the pulmonary bed from the right v ...
The main problem encountered in pulmonary artery banding is the difficulty in determining the optimal perimeter of the band, and sometime repeated surgical operations are required to adjust the band perimeter in order to control the pulmonary blood flow. T ...
In this thesis we study ventricular-arterial coupling in rodents under the influence of arterial stiffening and myocardial infarction (MI), combination of the two considered as a novel cardiovascular research model for diseased hearts pumping against an ag ...