Publication
A conditional glutamatergic synaptic vesicle marker for Drosophila
Related publications (111)
Principles of Network Plasticity in Neocortical Microcircuits
Synaptic plasticity underlies our ability to learn and adapt to the constantly changing environment. The phenomenon of synapses changing their efficacy in an activity-dependent manner is often studied in small groups of neurons in vitro or indirectly throu ...
EPFL2023Long-term plasticity induces sparse and specific synaptic changes in a biophysically detailed cortical model
Eilif Benjamin Muller, Michael Reimann, James Gonzalo King, Marwan Muhammad Ahmed Abdellah, Pramod Shivaji Kumbhar, András Ecker, Sirio Bolaños Puchet, James Bryden Isbister, Daniela Egas Santander, Jorge Blanco Alonso, Giuseppe Chindemi, Ioannis Magkanaris
Synaptic plasticity underlies the brain’s ability to learn and adapt. This process is often studied in small groups of neurons in vitro or indirectly through its effects on behavior in vivo. Due to the limitations of available experimental techniques, inve ...
2023A conditional GABAergic synaptic vesicle marker for Drosophila
Background: Throughout the animal kingdom, GABA is the principal inhibitory neurotransmitter of the nervous system. It is essential for maintaining the homeostatic balance between excitation and inhibition required for the brain to operate normally. Identi ...
2022The matricellular protein Drosophila Cellular Communication Network Factor is required for synaptic transmission and female fertility
Evelyne Ruchti, Brian Donal McCabe
Within the extracellular matrix, matricellular proteins are dynamically expressed nonstructural proteins that interact with cell surface receptors, growth factors, and proteases, as well as with structural matrix proteins. The cellular communication networ ...
Bethesda2022The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types
Sean Lewis Hill, Mohameth François Sy
The challenge of defining and cataloging the building blocks of the brain requires a standardized approach to naming neurons and organizing knowledge about their properties. The US Brain Initiative Cell Census Network, Human Cell Atlas, Blue Brain Project, ...
HUMANA PRESS INC2022Modelling and Refining Neuronal Circuits with Guidance Cues: Involvement of Semaphorins
The establishment of neuronal circuits requires neurons to develop and maintain appropriate connections with cellular partners in and out the central nervous system. These phenomena include elaboration of dendritic arborization and formation of synaptic co ...
MDPI2021Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2 alpha HRI kinase
Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying to unveil the ...
NATURE RESEARCH2021Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing
Carl Petersen, Sylvain Crochet, Célia Roxane Gasselin, Benoît Hohl
Fast synaptic transmission relies upon the activation of ionotropic receptors by neurotransmitter release to evoke postsynaptic potentials. Glutamate and GABA play dominant roles in driving highly dynamic activity in synaptically connected neuronal circuit ...
CELL PRESS2021Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing
Olivier Burri, Evelyne Ruchti, Brian Donal McCabe, Soumya Banerjee, Wei Jiao
The decline of neuronal synapses is an established feature of ageing accompanied by the diminishment of neuronal function, and in the motor system at least, a reduction of behavioural capacity. Here, we have investigated Drosophila motor neuron synaptic te ...
NATURE RESEARCH2021Distinguishing dopamine and calcium responses using XNA-nanotube sensors for improved neurochemical sensing
Ardemis Anoush Boghossian, Melania Reggente, Alice Judith Gillen, Alessandra Antonucci, Daniel Eduardo Morales Garza
To date, the engineering of single-stranded DNA-SWCNT (DNA-SWCNT) optical biosensors have largely focused on creating sensors for new applications with little focus on optimising existing sensors for in vitro and in vivo conditions. Recent studies have sho ...
2021