Mechanical Reinforcement of Hydrogels through Physical Crosslinks and Double Network Granular Architecture
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Supramolecular rubbers incorporating a large number of physical cross-links through cooperative hydrogen bonds display high self-healing properties but limited solvent and creep resistance due to the lack of chemical cross-links. Increasing both chemical c ...
This work addresses the development of composite materials that contain metallic load-bearing cords with the aim of combining outstanding mechanical performance with added functionality, including electrical conductivity, data transmission, and temperature ...
Mammalian cell behavior is strongly influenced by physical and chemical cues originating from the extracellular matrix (ECM). In vivo, ECM signals are displayed in a spatiotemporally complex fashion, often composed as gradients and in concentration profile ...
The in vitro recapitulation of tissue and organ function represents one of the main objectives
of tissue engineering. Developments in this field have numerous applications, from alleviating
the shortage of donor organs to providingmore representative pla ...
The nucleus pulposus of the intervertebral disc is a gelatinous viscous hydrogel that has an essential role in the mechanics of the intervertebral disc joint. The viscoelastic properties of the nucleus pulposus significantly change in the course of time an ...
Hydrogels are widely used in the biomedical field. Their main purposes are either to deliver biological active agents or to temporarily fill a defect until they degrade and are followed by new host tissue formation. However for this latter application, bio ...
The present invention relates to reinforced composite hydrogel based on a polymer blend and comprising a network of fibres, said polymer blend comprising UV sensitive molecules. It also relates to a process for preparing the reinforced composite hydrogel a ...
PEGDA hydrogels copolymerized with NVP using free-radical photopolymerization are used in biomedical applications. These networks consist of a poly(acrylate-co-vinyl pyrrolidone) backbone crosslinked with PEG chains whose crosslink density is dependent on ...
In recent years sophisticated biomaterials have made a significant impact on our understanding of cellular behavior, particularly in the fields of stem cell research and tissue engineering. Nevertheless, the promising potential of stem cells for regenerati ...
This thesis work focuses on applying microtechnology to produce three toolkits for life-sciences research. The first technique presented is nanostencil lithography for patterning cell adhesions. Nanostencil lithography is a shadow-mask micro and nanopatter ...