Publication
Solving the mystery of the missing plasmids in seventh pandemic Vibrio cholerae strains
Related publications (32)
Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance
Anne-Florence Raphaëlle Bitbol
While the biofilm growth mode conveys notable thriving advantages to bacterial populations, the mechanisms of biofilm formation are still strongly debated. Here, we investigate the remarkable spontaneous formation of regular spatial patterns during the gro ...
Royal Society of Chemistry (RSC)2020Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms
Mélanie Thérèse Marie Hannebelle
Mycobacterium tuberculosis, the etiological agent for the tuberculosis disease, is a bacterial pathogen thought to infect about a quarter of the global human population. It is the first cause of death among infectious diseases, and is most prevalent in low ...
EPFL2020Vibrio cholerae filamentation promotes chitin surface attachment at the expense of competition in biofilms
Collective behavior in spatially structured groups, or biofilms, is the norm among microbes in their natural environments. Though biofilm formation has been studied for decades, tracing the mechanistic and ecological links between individual cell morpholog ...
PNAS2019Single-cell studies of Mycobacterium smegmatis cell cycle using time-lapse fluorescence microscopy
Cell division is one of the most primordial cellular processes and is essential for life propagation. It is composed of crucial events, namely genome duplication, chromosomes segregation and membrane separation. Failure of these processes will have dramati ...
EPFL2019Rainfall as a driver of epidemic cholera: Comparative model assessments of the effect of intra-seasonal precipitation events
Andrea Rinaldo, Damiano Pasetto, Francisco Javier Perez Saez, Joseph Chadi Benoit Lemaitre, Carla Sciarra
The correlation between cholera epidemics and climatic drivers, in particular seasonal tropical rainfall, has been studied in a variety of contexts owing to its documented relevance. Several mechanistic models of cholera transmission have included rainfall ...
2019Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach
Bruno Lemaitre, Camilla Carla Alma Ceroni, Mark Austin Hanson, Anna Dostalova
Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading microorganisms. These short, cationic peptides have been implicated in many biological processes, primarily involving innate immunity. In vitro studies have shown AMPs kill bac ...
Cambridge University Press2019Two nanomachines drive evolution in diverse Vibrio species
Horizontal gene transfer (HGT) has a major impact on bacterial evolution, leading to acquisition or deletion of genes and gene clusters, including those encoding antibiotic resistances and virulence factors. HGT therefore contributes to pathogen emergence, ...
EPFL2019Eco-Evolutionary Dynamics Linked to Horizontal Gene Transfer in Vibrios
Melanie Blokesch, Frédérique Marie Jeanne Le Roux
Vibrio is a genus of ubiquitous heterotrophic bacteria found in aquatic environments. Although they are a small percentage of the bacteria in these environments, vibrios can predominate during blooms. Vibrios also play important roles in the degradation of ...
2018Modeling Key Drivers of Cholera Transmission Dynamics Provides New Perspectives for Parasitology
Andrea Rinaldo, Melanie Blokesch, Enrico Bertuzzo, Lorenzo Mari, Marino Gatto
Hydroclimatological and anthropogenic factors are key drivers of waterborne disease transmission. Information on human settlements and host mobility on waterways along which pathogens and hosts disperse, and relevant hydroclimatological processes, can be a ...
Elsevier2017Circulation of a Quorum-Sensing-Impaired Variant of Vibrio cholerae Strain C6706 Masks Important Phenotypes
Melanie Blokesch, Sandrine Stutzmann
Vibrio cholerae, the causative agent of cholera, is a model organism for studying virulence regulation, biofilm formation, horizontal gene transfer, and the cell-to-cell communication known as quorum sensing (QS). As in any research field, discrepancies be ...
Amer Soc Microbiology2016