Biochemical cascadeA biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when initiated by a stimulus. This stimulus, known as a first messenger, acts on a receptor that is transduced to the cell interior through second messengers which amplify the signal and transfer it to effector molecules, causing the cell to respond to the initial stimulus. Most biochemical cascades are series of events, in which one event triggers the next, in a linear fashion.
Metabolic pathwayIn biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reactions catalyzed by enzymes. In most cases of a metabolic pathway, the product of one enzyme acts as the substrate for the next. However, side products are considered waste and removed from the cell. These enzymes often require dietary minerals, vitamins, and other cofactors to function.
MetabolismMetabolism (məˈtæbəlɪzəm, from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments.
IP addressAn Internet Protocol address (IP address) is a numerical label such as 192.0.2.1 that is connected to a computer network that uses the Internet Protocol for communication. An IP address serves two main functions: network interface identification, and location addressing. Internet Protocol version 4 (IPv4) defines an IP address as a 32-bit number. However, because of the growth of the Internet and the depletion of available IPv4 addresses, a new version of IP (IPv6), using 128 bits for the IP address, was standardized in 1998.
Multicast addressA multicast address is a logical identifier for a group of hosts in a computer network that are available to process datagrams or frames intended to be multicast for a designated network service. Multicast addressing can be used in the link layer (layer 2 in the OSI model), such as Ethernet multicast, and at the internet layer (layer 3 for OSI) for Internet Protocol Version 4 (IPv4) or Version 6 (IPv6) multicast. IPv4 multicast addresses are defined by the most-significant bit pattern of 1110.
Warburg effect (oncology)In oncology, the Warburg effect (ˈvɑrbʊərg) is the observation that most cancer cells produce energy predominantly not through the 'usual' citric acid cycle and oxidative phosphorylation in the mitochondria as observed in normal cells, but through a less efficient process of 'aerobic glycolysis' consisting of a high level of glucose uptake and glycolysis followed by lactic acid fermentation taking place in the cytosol, not the mitochondria, even in the presence of abundant oxygen.
Link-local addressIn computer networking, a link-local address is a unicast network address that is valid only for communications within the subnetwork that the host is connected to. Link-local addresses are most often assigned automatically with a process known as stateless address autoconfiguration or link-local address autoconfiguration, also known as automatic private IP addressing (APIPA) or auto-IP. Link-local addresses are not guaranteed to be unique beyond their network segment.
IPv4 address exhaustionIPv4 address exhaustion is the depletion of the pool of unallocated IPv4 addresses. Because the original Internet architecture had fewer than 4.3 billion addresses available, depletion has been anticipated since the late 1980s, when the Internet started experiencing dramatic growth. This depletion is one of the reasons for the development and deployment of its successor protocol, IPv6. IPv4 and IPv6 coexist on the Internet.
IPv6 addressAn Internet Protocol Version 6 address (IPv6 address) is a numeric label that is used to identify and locate a network interface of a computer or a network node participating in a computer network using IPv6. IP addresses are included in the packet header to indicate the source and the destination of each packet. The IP address of the destination is used to make decisions about routing IP packets to other networks. IPv6 is the successor to the first addressing infrastructure of the Internet, Internet Protocol version 4 (IPv4).
Basal metabolic rateBasal metabolic rate (BMR) is the rate of energy expenditure per unit time by endothermic animals at rest. It is reported in energy units per unit time ranging from watt (joule/second) to ml O2/min or joule per hour per kg body mass J/(h·kg). Proper measurement requires a strict set of criteria to be met. These criteria include being in a physically and psychologically undisturbed state and being in a thermally neutral environment while in the post-absorptive state (i.e., not actively digesting food).