Neurotransmitter receptorA neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside of the cell, such as a neurotransmitter, can bump into the cell's membrane, in which there are receptors. If a neurotransmitter bumps into its corresponding receptor, they will bind and can trigger other events to occur inside the cell. Therefore, a membrane receptor is part of the molecular machinery that allows cells to communicate with one another.
Neural oscillationNeural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons.
Supraesophageal ganglionThe supraesophageal ganglion (also "supraoesophageal ganglion", "arthropod brain" or "microbrain") is the first part of the arthropod, especially insect, central nervous system. It receives and processes information from the first, second, and third metameres. The supraesophageal ganglion lies dorsal to the esophagus and consists of three parts, each a pair of ganglia that may be more or less pronounced, reduced, or fused depending on the genus: The protocerebrum, associated with the eyes (compound eyes and ocelli).
Conditional sentenceConditional sentences are natural language sentences that express that one thing is contingent on something else, e.g. "If it rains, the picnic will be cancelled." They are so called because the impact of the main clause of the sentence is conditional on the dependent clause. A full conditional thus contains two clauses: a dependent clause called the antecedent (or protasis or if-clause), which expresses the condition, and a main clause called the consequent (or apodosis or then-clause) expressing the result.
Catechol-O-methyltransferaseCatechol-O-methyltransferase (COMT; ) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. Two isoforms of COMT are produced: the soluble short form (S-COMT) and the membrane bound long form (MB-COMT).
Grammatical moodIn linguistics, grammatical mood is a grammatical feature of verbs, used for signaling modality. That is, it is the use of verbal inflections that allow speakers to express their attitude toward what they are saying (for example, a statement of fact, of desire, of command, etc.). The term is also used more broadly to describe the syntactic expression of modality – that is, the use of verb phrases that do not involve inflection of the verb itself.
GabapentinoidGabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) (i.e., GABA analogues) which block α2δ subunit-containing voltage-dependent calcium channels (VDCCs). This site has been referred to as the gabapentin receptor (α2δ subunit), as it is the target of the drugs gabapentin and pregabalin. Clinically used gabapentinoids include gabapentin, pregabalin, and mirogabalin, as well as a gabapentin prodrug, gabapentin enacarbil.
Irrealis moodIn linguistics, irrealis moods (abbreviated ) are the main set of grammatical moods that indicate that a certain situation or action is not known to have happened at the moment the speaker is talking. This contrasts with the realis moods. Every language has grammatical ways of expressing unreality. Linguists tend to reserve the term "irrealis" for particular morphological markers or clause types. Many languages with irrealis mood make further subdivisions between kinds of irrealis moods.
PregabalinPregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic and anxiolytic medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless leg syndrome, opioid withdrawal and generalized anxiety disorder (GAD). Pregabalin also has antiallodynic properties. Its use in epilepsy is as an add-on therapy for partial seizures. It is a gabapentinoid medication and acts by inhibiting certain calcium channels. When used before surgery, it reduces pain but results in greater sedation and visual disturbances.
