Clinical trialClinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought.
Population densityPopulation density (in agriculture: standing stock or plant density) is a measurement of population per unit land area. It is mostly applied to humans, but sometimes to other living organisms too. It is a key geographical term. In simple terms, population density refers to the number of people living in an area per square kilometre, or other unit of land area. Population density is population divided by total land area, sometimes including seas and oceans, as appropriate.
Avoidant/restrictive food intake disorderAvoidant/restrictive food intake disorder (ARFID) is an eating disorder in which people avoid eating or eat only a very narrow range of foods. This can be either due to the sensory characteristics of food, such as its appearance, smell, texture, or taste, or due to fear of negative consequences such as choking or vomiting. Others might show no interest in eating or food.
Adaptive design (medicine)In an adaptive design of a clinical trial, the parameters and conduct of the trial for a candidate drug or vaccine may be changed based on an interim analysis. Adaptive design typically involves advanced statistics to interpret a clinical trial endpoint. This is in contrast to traditional single-arm (i.e. non-randomized) clinical trials or randomized clinical trials (RCTs) that are static in their protocol and do not modify any parameters until the trial is completed.
