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Gentle nano-electrospray ion source for reliable and efficient generation of microsolvated ions
Related publications (49)
Standard-Free Quantification of Dicarboxylic Acids: Case Studies with Salt-Rich Effluents and Serum
Christian Ludwig, Daniil Salionov, Sasa Bjelic
The present study evaluates the ionization efficiency (IE) of linear and branched C2–C14 dicarboxylic acids (DCAs) by electrospray ionization (ESI) under different conditions. The influence of the concentration of organic modifier (MeOH); mobile phase addi ...
2022Diurnal evolution of negative atmospheric ions above the boreal forest: from ground level to the free troposphere
At SMEAR II research station in Hyytiala, located in the Finnish boreal forest, the process of new particle formation and the role of ions has been investigated for almost 20 years near the ground and at canopy level. However, above SMEAR II, the vertical ...
COPERNICUS GESELLSCHAFT MBH2022First operations with caesium of the negative ion source SPIDER
Riccardo Agnello, Michele Fadone, Alberto Ferro
The negative-ion based neutral beam injector for heating and current drive of the ITER plasma (ITER HNB) is under development, at present focusing on the optimization of the full-scale plasma source in the SPIDER test stand. The production of H- or D- ions ...
2022Charging and ion ejection dynamics of large helium nanodroplets exposed to intense femtosecond soft X-ray pulses
Christoph Bostedt, Camila Bacellar Cases Da Silveira, Daniela Rupp
Ion ejection from charged helium nanodroplets exposed to intense femtosecond soft X-ray pulses is studied by single-pulse ion time-of-flight (TOF) spectroscopy in coincidence with small-angle X-ray scattering. Scattering images encode the droplet size and ...
SPRINGER HEIDELBERG2021Coincidence imaging spectroscopy of extreme-ultraviolet photoionisation processes in molecules and clusters
Presented here is the design, construction and commissioning of a coincidence imaging spectroscopy endstation coupled to the Harmonium high-harmonic generation (HHG) extreme-ultraviolet photon source at the Lausanne Centre for Ultrafast Science. The endsta ...
EPFL2021Nonlinear kinetic simulation study of the ion-ion streaming instability in single- and multi-ion species plasmas
The nonlinear evolution of the ion-ion streaming instability (IISI) is studied using numerical techniques novel to this problem that afford direct insight into the evolution of the particle distributions of each species. During the linear phase of the inst ...
AMER INST PHYSICS2021New ionization and tagging methods for mass spectrometry
Mass spectrometry (MS) is an essential detection tool in bioanalytical chemistry owing to its exceptional selectivity and sensitivity, paired with rapid analyte identification and quantification. In this thesis, two classical MS and a newly developed ioniz ...
EPFL2017Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity
Paul Joseph Dyson, Laure Menin, Luc Patiny
RAPTA compounds, ([Ru(eta(6)-arene)(PTA)Cl-2], PTA = 1,3,5-triaza-7-phosphaadamantane), have been reported to overcome drug resistance in cisplatin resistant cells. However, the exact mechanism of these complexes is still largely unexplored. In this study, ...
Elsevier2017Method and apparatus for the analysis of molecules using mass spectrometry and optical spectroscopy
Vladimir Kopysov, Oleg Boyarkine
A method of analyzing molecules enabling chemical, structural and isomeric or conformational identification of the molecules, particularly in a stream from a chromatographic separation, comprising: generating ions from a sample of molecules to be analyzed; ...
2016Novel Approaches in Cold Ion Spectroscopy for Structural Characterization of Biomolecules in the Gas Phase
Mass spectrometry is a powerful analytical technique, which has become invaluable across a wide range of scientific fields, such as "omics" sciences (e.g., proteomics), doping control and forensic sciences, drug development, environmental analysis, geologi ...
EPFL2016