The Function of Two Radical-SAM Enzymes, HcgA and HcgG, in the Biosynthesis of the [Fe]-Hydrogenase Cofactor
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Mycobacterium tuberculosis has a remarkable ability to persist within the human host as a clinically inapparent or chronically active infection. Fatty acids are thought to be an important carbon source used by the bacteria during long term infection. Catab ...
Lipids are major constituents of the cell, implicated with its functional and structural properties, along with a number of chronic diseases. Applying computational techniques with systematic modeling of lipids can provide insights about mechanisms that re ...
Tetrachloroethene (PCE) reductive dehalogenases are the key catalysts in the respiratory chain of dehalorespiring microorganisms, where they act as the terminal electron-accepting enzymes in the process. On protein level, reductive dehalogenases have been ...
Enzymes possessing the capacity to oxidize molecular hydrogen have developed convergently three class of enzymes leading to: [FeFe]-, [NiFe]-, and [FeS]-cluster-free hydrogenases. They differ in the composition and the structure of the active site metal ce ...