Publication
Implementation of a flavin biosynthesis operon improves extracellular electron transfer in bioengineered Escherichia coli
Related publications (34)
Redox Properties of Flavin in BLUF and LOV Photoreceptor Proteins from Hybrid QM/MM Molecular Dynamics Simulation
Flavins play an important role in many oxidation and reduction processes in biological systems. For example, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) are common cofactors found in enzymatic proteins that use the special redox prope ...
Amer Chemical Soc2024Engineering extracellular electron transfer for enhanced energy harvesting in microbial electrochemical devices
Microorganisms known as exoelectrogens evolved the ability of transporting electrons across insulating biological membranes. In a physiological context, this enables respiration on extracellular electron acceptors and electron transfer to other organisms. ...
EPFL2023Insights into the microbial reduction of pentavalent and hexavalent uranium species by Shewanella oneidensis MR-1
Margaux Camille Andréa Molinas
Decades of uranium-related activities such as ore mining, nuclear power generation, weapon manufacture, storage of nuclear wastes, have contributed to the release of U in the environment. U occurrence is concerning, since in surface environments, U is typi ...
EPFL2021Tailored extracellular electron transfer pathways enhance the electroactivity of Escherichia coli
Ardemis Anoush Boghossian, Melania Reggente, Mohammed Mouhib, Nils Schürgers, Lin Li
Extracellular electron transfer (EET) engineering in Escherichia coli holds great potential for bioremediation, energy and electrosynthesis applications fueled by readily available organic substrates. Due to its vast metabolic capabilities and availability ...
2021New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis
Stewart Cole, Andrej Benjak, Anthony Vocat, Jérémie Piton, Shi-Yan Caroline Foo, Andréanne Lupien
The emergence of multi-drug (MDR-TB) and extensively-drug resistant tuberculosis (XDR-TB) is a major threat to the global management of tuberculosis (TB) worldwide. New chemical entities are of need to treat drug-resistant TB. In this study, the mode of ac ...
2020Spin cascade and doming in ferric hemes: Femtosecond X-ray absorption and X-ray emission studies
Majed Chergui, Oliviero Cannelli, Christopher Alexander Arrell, Wojciech Gawelda, Giulia Fulvia Mancini, Frederico Alves Lima, Camila Bacellar Cases Da Silveira, Dominik Kinschel, Rebecca Ann Ingle, Jérémy Raymond Jean Maurice Rouxel, Samuel Menzi
The structure-function relationship is at the heart of biology, and major protein deformations are correlated to specific functions. For ferrous heme proteins, doming is associated with the respiratory function in hemoglobin and myoglobins. Cytochrome c (C ...
NATL ACAD SCIENCES2020Mechanism(s) of electron transfer and metabolic changes during iron reduction by Clostridium acetobutylicum
Microorganisms catalyze many of the redox transformations driving the iron cycle in the geosphere. For instance, iron cycling includes the reduction of solid-phase and soluble ferric iron (Fe(III)) to ferrous iron (Fe(II)). However, in order to reduce soli ...
EPFL2019The membrane-bound C subunit of reductive dehalogenases: topology analysis and reconstitution of the FMN-binding domain of PceC
Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet, Aamani Rupakula Boyanapalli
Organohalide respiration (OHR) is the energy metabolism of anaerobic bacteria able to use halogenated organic compounds as terminal electron acceptors. While the terminal enzymes in OHR, so-called reductive dehalogenases, are well-characterized, the identi ...
Frontiers Media SA2018The Membrane-Bound C Subunit of Reductive Dehalogenases: Topology Analysis and Reconstitution of the FMN-Binding Domain of PceC
Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet, Aamani Rupakula Boyanapalli
Organohalide respiration (OHR) is the energy metabolism of anaerobic bacteria able to use halogenated organic compounds as terminal electron acceptors. While the terminal enzymes in OHR, so-called reductive dehalogenases, are well-characterized, the identi ...
2018RdhC, a family of membrane-bound flavoproteins involved in electron transfer in organohalide respiration ?
Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet
Organohalide respiration (OHR) is a bacterial energy metabolism making use of halogenated compounds – like tetrachloroethene (PCE), a major pollutant – as terminal electron acceptors. Three models of electron transport chain exist for OHR [1], however many ...
2018