SenescenceSenescence (sɪˈnɛsəns) or biological aging is the gradual deterioration of functional characteristics in living organisms. The word senescence can refer to either cellular senescence or to senescence of the whole organism. Organismal senescence involves an increase in death rates and/or a decrease in fecundity with increasing age, at least in the latter part of an organism's life cycle. Senescence is the inevitable fate of almost all multicellular organisms with germ-soma separation, but it can be delayed.
X.Org ServerX.Org Server is the free and open-source implementation of the X Window System display server stewarded by the X.Org Foundation. Implementations of the client-side X Window System protocol exist in the form of X11 libraries, which serve as helpful APIs for communicating with the X server. Two such major X libraries exist for X11. The first of these libraries was Xlib, the original C language X11 API, but another C language X library, XCB, was created later in 2001.
Evolution of ageingEnquiry into the evolution of ageing, or aging, aims to explain why a detrimental process such as ageing would evolve, and why there is so much variability in the lifespans of organisms. The classical theories of evolution (mutation accumulation, antagonistic pleiotropy, and disposable soma) suggest that environmental factors, such as predation, accidents, disease, and/or starvation, ensure that most organisms living in natural settings will not live until old age, and so there will be very little pressure to conserve genetic changes that increase longevity.
OpenOffice.orgOpenOffice.org (OOo), commonly known as OpenOffice, is a discontinued open-source office suite. Active successor projects include LibreOffice (the most actively developed), Apache OpenOffice, Collabora Online (enterprise ready LibreOffice) and NeoOffice (commercial, and available only for macOS). OpenOffice was an open-sourced version of the earlier StarOffice, which Sun Microsystems acquired in 1999 for internal use. Sun open-sourced the OpenOffice suite in July 2000 as a competitor to Microsoft Office, releasing version 1.
GNU General Public LicenseThe GNU General Public License (GNU GPL or simply GPL) is a series of widely used free software licenses that guarantee end users the four freedoms to run, study, share, and modify the software. The license was the first copyleft for general use and was originally written by the founder of the Free Software Foundation (FSF), Richard Stallman, for the GNU Project. The license grants the recipients of a computer program the rights of the Free Software Definition.
Natural killer cellNatural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system that belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. The role of NK cells is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to virus-infected cell and other intracellular pathogens acting at around 3 days after infection, and respond to tumor formation.
Free-radical additionIn organic chemistry, free-radical addition is an addition reaction which involves free radicals. The addition may occur between a radical and a non-radical, or between two radicals. The basic steps with examples of the free-radical addition (also known as radical chain mechanism) are: Initiation by a radical initiator: A radical is created from a non-radical precursor.
Life extensionLife extension is the concept of extending the human lifespan, either modestly through improvements in medicine or dramatically by increasing the maximum lifespan beyond its generally-settled limit of 125 years. Several researchers in the area, along with "life extensionists", "immortalists" or "longevists" (those who wish to achieve longer lives themselves), postulate that future breakthroughs in tissue rejuvenation, stem cells, regenerative medicine, molecular repair, gene therapy, pharmaceuticals, and organ replacement (such as with artificial organs or xenotransplantations) will eventually enable humans to have indefinite lifespans (agerasia) through complete rejuvenation to a healthy youthful condition.
Wild typeThe wild type (WT) is the phenotype of the typical form of a species as it occurs in nature. Originally, the wild type was conceptualized as a product of the standard "normal" allele at a locus, in contrast to that produced by a non-standard, "mutant" allele. "Mutant" alleles can vary to a great extent, and even become the wild type if a genetic shift occurs within the population. Continued advancements in genetic mapping technologies have created a better understanding of how mutations occur and interact with other genes to alter phenotype.
Comparison of free and open-source software licensesThis comparison only covers software licenses which have a linked Wikipedia article for details and which are approved by at least one of the following expert groups: the Free Software Foundation, the Open Source Initiative, the Debian Project and the Fedora Project. For a list of licenses not specifically intended for software, see List of free-content licences. FOSS stands for "Free and Open Source Software". There is no one universally agreed-upon definition of FOSS software and various groups maintain approved lists of licenses.
