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Two antagonistic response regulators control Pseudomonas aeruginosa polarization during mechanotaxis
Related publications (34)
Beyond the ultradeep frontier fields and legacy observations (BUFFALO): a high-resolution strong plus weak-lensing view of Abell 370
David Richard Harvey, Mathilde Jauzac
The HST treasury programme BUFFALO provides extended wide-field imaging of the six Hubble Frontier Fields galaxy clusters. Here we present the combined strong and weak-lensing analysis of Abell 370, a massive cluster at z = 0.375. From the reconstructed to ...
OXFORD UNIV PRESS2023Characterization of Pseudomonas aeruginosa mechanosensing through label-free imaging of type IV pili
Bacteria are ubiquitously found in all sorts of environment. They're found in the ocean, soil, or even in our guts or on our skin. Independently of their niche, they can transition from a planktonic state were they freely swim in an aqueous environment to ...
EPFL2022« À l’Ouest, du nouveau ». Paysage commercial urbain à l’épreuve de la transition numérique
Dans le district de l’Ouest Lausannois s’annonce un vaste chantier, celui de la ville durable. La question commerciale semble étonnamment peu traitée, voire absente des documents de planification de ce morceau de ville en devenir. Pourtant, la transition n ...
2021Mechanotaxis directs Pseudomonas aeruginosa twitching motility
Alexandre Louis André Persat, Lorenzo Anton-Louis Talà, Xavier Jean-Yves Pierrat, Jose Negrete Jr, Joanne Netter Engel, Marco Julian Kühn
The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellu-lar filaments called type IV pili (T4P). Single cells twitch by sequen-tial T4P extension, attachment, and retraction. How single ...
NATL ACAD SCIENCES2021From Data to Decisions: Distributionally Robust Optimization is Optimal
Daniel Kuhn, Peyman Mohajerin Esfahani
We study stochastic programs where the decision-maker cannot observe the distribution of the exogenous uncertainties but has access to a finite set of independent samples from this distribution. In this setting, the goal is to find a procedure that transfo ...
2020Scalable Stochastic Optimization: Scenario Reduction with Guarantees
Stochastic optimization is a popular modeling paradigm for decision-making under uncertainty and has a wide spectrum of applications in management science, economics and engineering. However, the stochastic optimization models one faces in practice are int ...
EPFL2020Sublinear Bounds on the Distinguishing Advantage for Multiple Samples
The maximal achievable advantage of a (computationally unbounded) distinguisher to determine whether a source is distributed according to distribution or , when given access to one sample of , is characterized by the statistical distance ...
Springer, Cham2020Pseudomonas aeruginosa orchestrates twitching motility by sequential control of type IV pili movements
Alexandre Louis André Persat, Lorenzo Anton-Louis Talà
Prokaryotes have the ability to walk on surfaces using type IV pili (TFP), a motility mechanism known as twitching(1,2). Molecular motors drive TFP extension and retraction, but whether and how these movements are coordinated is unknown(3). Here, we reveal ...
NATURE PUBLISHING GROUP2019The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase
Melanie Blokesch, Sandrine Stutzmann, Candice Stoudmann, David William Adams, Jorge André Matias Pereira
Type IV pili are dynamic cell surface appendages found throughout the bacteria. The ability of these structures to undergo repetitive cycles of extension and retraction underpins their crucial roles in adhesion, motility and natural competence for transfor ...
2019Modeling Macroroughness Contribution to Fish Habitat Suitability Curves
Paolo Perona, Holly Jayne Oldroyd, Amin Niayifar
Improved water management strategies necessitate a solid understanding of environmental impacts associated with various flow release policies. Habitat suitability models use hydrodynamic simulations to generate weighted usable area curves, which are useful ...
2018