Publication
Plasma biomarkers for Alzheimer's disease: a field-test in a memory clinic
Related publications (32)
Classification of patients with cardiac amyloidosis using machine learning models on Italian electronic clinical health records
Silvestro Micera, Sara Mazzucato
Amyloidosis refers to a range of medical conditions in which misshapen proteins accumulate in various organs and tissues, forming insoluble fibrils. Cardiac amyloidosis is frequently linked to the buildup of misfolded transthyretin (TTR) or immunoglobulin ...
New York2023Monitoring of Protein and pH Levels in Human Biofluids using FD-SOI Silicon Nanowire Arrays
Medical research and technological advancements are heading towards tailored healthcare approaches that prioritize individual needs, allowing for more accurate diagnoses, more effective treatments, and better patient outcomes overall. One such approach is ...
EPFL2023Re-focusing explainability in medicine
Using artificial intelligence to improve patient care is a cutting-edge methodology, but its implementation in clinical routine has been limited due to significant concerns about understanding its behavior. One major barrier is the explainability dilemma a ...
2022Nanoparticle-enhanced Imaging Based Plasmonic Biosensor
Efficient medical care fundamentally relies on the ability to provide a timely and accurate diagnosis. Thanks to advances in biomedical research, specific molecules called diagnostic molecular biomarkers have been discovered in the human body that help ind ...
EPFL2020Novel PDE6B Mutation Presenting with Retinitis Pigmentosa - A Case Series of Three Patients
Background Retinitis pigmentosa (RP) affects 2.5 million people worldwide. Increased identification of causative gene defects and the increasing possibility of treatment necessitates better knowledge of phenotype-genotype correlations to help identify pati ...
2019A nation-wide initiative for brain imaging and clinical phenotype data federation in Swiss university memory centres
Jean-Philippe Thiran, Bogdan Draganski
Purpose of review The goal of our nation-wide initiative is to provide clinicians intuitive and robust tools for accurate diagnosis, therapy monitoring and prognosis of cognitive decline that is based on large-scale multidomain data. Recent findings We des ...
LIPPINCOTT WILLIAMS & WILKINS2019PET-based prognostic survival model after radiotherapy for head and neck cancer
Adrien Raphaël Depeursinge, Xin Sun
PurposeThe aims of this multicentre retrospective study of locally advanced head and neck cancer (LAHNC) treated with definitive radiotherapy were to (1) identify positron emission tomography (PET)-F-18-fluorodeoxyglucose (F-18-FDG) parameters correlated w ...
SPRINGER2019Phospho-S129 Alpha-Synuclein Is Present in Human Plasma but Not in Cerebrospinal Fluid as Determined by an Ultrasensitive Immunoassay
Hilal Lashuel, Lara Petricca, Sean Michael Deguire
Accumulation and aggregation of misfolded alpha-synuclein is believed to be a cause of Parkinson's disease (PD). Phosphorylation of alpha-synuclein at S129 is known to be associated with the pathological misfolding process, but efforts to investigate the r ...
2019Microwave Imaging of Brain Stroke
Brain stroke is an age-related illness which has become a major issue in our ageing societies. Early diagnosis and treatment are of high importance for the full recovery of the patient, as reminded in Anglo-Saxon countries by the abbreviation FAST (Face, A ...
EPFL2018In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose
Rolf Gruetter, Cristina Ramona Cudalbu, Bernard Lanz, Carole Poitry-Yamate, Marta Lai, Corina Mihaela Berset
In vivo (13)C magnetic resonance spectroscopy (MRS) enables the investigation of cerebral metabolic compartmentation while, e.g. infusing (13)C-labeled glucose. Metabolic flux analysis of (13)C turnover previously yielded quantitative information of glutam ...
2018