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Hemoglobin-stabilized gold nanoclusters displaying oxygen transport ability, self-antioxidation, auto-fluorescence properties and long-term storage potential
Related publications (37)
In vitro-transfusional model for red-blood-cell study: the advantage of lowering hematocrit
Gerardo Turcatti, David Crettaz, Michel Prudent, Manon Sandra Bardyn
Background - Thequalityof red blood cells (RBCs) stored in red cell concentrates (RCCs) is influenced by processing, storage and donor characteristics, and can have a clinical impact on transfused patients. To evaluate RBC properties and their potential im ...
Simtipro Srl2023Ultraflexible flow directed device and system
Mahmut Selman Sakar, Pietro Luciano Jakobus Dirix
A flow directed device adapted to be guided by a fuid, such as blood, flow within a tubular structure such as a blood vessel is disclosed, said device comprising a proximal end (100), a distal end (101) and an elongated body (102) in between defining a lon ...
2021Tailoring the redox-active transition metal content to enhance cycling stability in cation-disordered rock-salt oxides
Corsin Battaglia, Chunyang Zhang, Yong Yang, Yining Li
Lithium-excess cation-disordered rock-salt oxides (DRXs) are investigated intensively as cathode materials for future lithium-ion batteries combining cationic and anionic redox reactions. However, the lattice oxygen redox can cause severe oxygen release re ...
ELSEVIER2021Pharmacokinetics and biodistribution study of self-assembled Gd-micelles demonstrating blood-pool contrast enhancement for MRI
Lothar Helm, Yohan Van de Looij
Magnetic resonance angiography (MRA) requires the use of contrast agents (CAs) to enable accurate diagnosis. There are currently no CAs on the market with appropriate pharmacokinetic (PK) parameters, namely long persistence in the blood, that can be easily ...
2019Semisynthetic sensor proteins enable metabolic assays at the point of care
Kai Johnsson, Rudolf Griss, Qiuliyang Yu, Lin Xue, Julien Hiblot
Monitoring metabolites at the point of care could improve the diagnosis and management of numerous diseases. Yet for most metabolites, such assays are not available. We introduce semisynthetic, light-emitting sensor proteins for use in paper-based metaboli ...
AMER ASSOC ADVANCEMENT SCIENCE2018Microdevice-integrated immunoassays for Point-of-Care Therapeutic Drug Monitoring
A significant number of drugs exhibit narrow therapeutic windows and high inter-individual pharmacokinetic variability. In such cases, Therapeutic Drug Monitoring (TDM) is compulsory in order to optimize the efficacy of the drug while avoiding adverse effe ...
EPFL2018Quantification of stored red blood cell fluctuations by time-lapse holographic cell imaging
Gerardo Turcatti, Benjamin Rappaz, Pierre Marquet, Michel Prudent, Manon Sandra Bardyn
We propose methods to quantitatively calculate the fluctuation rate of red blood cells with nanometric axial and millisecond temporal sensitivity at the single-cell level by using time-lapse holographic cell imaging. For this quantitative analysis, cell me ...
OPTICAL SOC AMER2018The antioxidant capacity of erythrocyte concentrates is increased during the first week of storage and correlated with the uric acid level
Hubert Girault, Niels Erik Lion, Andreas Stephan Lesch, Fernando Cortes Salazar, Michel Prudent, Sunny Isaïe Maye, Manon Sandra Bardyn
Background and Objectives: Red blood cells (RBCs) suffer from lesions during cold storage, depending in part on their ability to counterbalance oxidative stress by activating their antioxidant defence. The aim of this study was to monitor the antioxidant p ...
Wiley-Blackwell2017Microdevice for Sedimentation-based Separation of Blood Microsamples at the Point of Collection
Laboratory blood testing plays a central role in current diagnostics and therapeutical decisions. Thus, errors have a direct impact on care quality and cost. The majority of errors occur in the pre-analytical phase, when samples are collected, stored and p ...
EPFL2017Red blood cells ageing markers: a multi-parametric analysis
Gerardo Turcatti, Niels Erik Lion, Benjamin Rappaz, David Crettaz, Michel Prudent, Manon Sandra Bardyn
Background. Red blood cells collected in citrate-phosphate-dextrose can be stored for up to 42 days at 4 degrees C in saline-adenine-glucose-mannitol additive solution. During this controlled, but nevertheless artificial, ex vivo ageing, red blood cells ac ...
Simti Servizi Srl2017