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The Mind Behind the Hebbian Synapse Donald O Hebb

Shriya Palchaudhuri

How do neurons orchestrate behaviour? Let us trace our footsteps back to one of the first hypotheses proposing an alliance between the brain and behaviour. This article trace Donald Hebb's life, and how, in the neurophysiology milieu of the 20th century, h ...

SPRINGER INDIA2020

Stability of working memory in continuous attractor networks under the control of short-term plasticity

Wulfram Gerstner, Alexander Kevin Seeholzer, Moritz Deger

Continuous attractor models of working-memory store continuous-valued information in continuous state-spaces, but are sensitive to noise processes that degrade memory retention. Short-term synaptic plasticity of recurrent synapses has previously been shown ...

PUBLIC LIBRARY SCIENCE2019

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Synaptic changes induced by neural activity need to be consolidated to maintain memory over a timescale of hours. In experiments, synaptic consolidation can be induced by repeating a stimulation protocol several times and the effectiveness of consolidation ...

FRONTIERS MEDIA SA2019

Continuous attractor working memory and provenance of channel models

Alexander Kevin Seeholzer

The brain is a complex biological system composed of a multitude of microscopic processes, which together give rise to computational abilities observed in everyday behavior. Neuronal modeling, consisting of models of single neurons and neuronal networks at ...

EPFL2017

Hebbian plasticity requires compensatory processes on multiple timescales

Wulfram Gerstner, Friedemann Zenke

We review a body of theoretical and experimental research on Hebbian and homeostatic plasticity, starting from a puzzling observation: while homeostasis of synapses found in experiments is a slow compensatory process, most mathematical models of synaptic p ...

Royal Soc2017

Prospective Coding by Spiking Neurons

Johanni Michael Brea, Walter Senn

Animals learn to make predictions, such as associating the sound of a bell with upcoming feeding or predicting a movement that a motor command is eliciting. How predictions are realized on the neuronal level and what plasticity rule underlies their learnin ...

Public Library of Science2016

Diverse synaptic plasticity mechanisms orchestrated to form and retrieve memories in spiking neural networks

Wulfram Gerstner, Friedemann Zenke

Synaptic plasticity, the putative basis of learning and memory formation, manifests in various forms and across different timescales. Here we show that the interaction of Hebbian homosynaptic plasticity with rapid non-Hebbian heterosynaptic plasticity is, ...

Nature Publishing Group2015

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Bursts of activity in networks of neurons are thought to convey salient information and drive synaptic plasticity. Here we report that network bursts also exert a profound effect on Spike-Timing-Dependent Plasticity (STDP). In acute slices of juvenile rat ...

2015

Memory formation and recall in recurrent spiking neural networks

Friedemann Zenke

Our brain has the capacity to analyze a visual scene in a split second, to learn how to play an instrument, and to remember events, faces and concepts. Neurons underlie all of these diverse functions. Neurons, cells within the brain that generate and trans ...

EPFL2014

Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellula ...

Nature Publishing Group2014