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Fine Arts in Transition: An Operative Research and Teaching Approach between Analogue and Digital

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The archive of science is a place where scientific practices are sedimented in the form of drafts, protocols of rejected hypotheses and failed experiments, obsolete instruments, outdated visualizations and other residues. Today, just as science goes more a ...

EPFL2024

The course analyses a selection of case studies on selected topics to describe how human agency can respond, prevent or mitigate ethical issues by reframing these as opportunities for innovation. This analysis provides indication on what could be a good pr ...

2024

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Connectivity between the hyporheic zone and the flow is essential for the development of benthos and the reproductive success of spawning fish. The infiltration of fine sediment leads to clogging of the riverbed, reducing porosity and vertical water exchan ...

2023

Individual and combined benefits of different nonequilibrium proofreading mechanisms

Paolo De Los Rios, Daniel Maria Busiello, Stefano Zamuner, Adélaïde Alice Mohr

Genome duplication, transcription, and translation are among many crucial cellular processes that need to be performed with high fidelity. However, those extremely low error rates cannot be explained with simple equilibrium thermodynamic considerations. Th ...

College Pk2023

Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive

Konstantin Popadin

The resilience of the mitochondrial genome (mtDNA) to a high mutational pressure depends, in part, on negative purifying selection in the germline. A paradigm in the field has been that such selection, at least in part, takes place in primordial germ cells ...

London2023

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Background While specialization plays an essential role in how scientific research is pursued, we understand little about its effects on a researcher's impact and career. In particular, the extent to which one specializes within their chosen fields likely ...

BMC2022

“Methodological Criss-Crossing”: A Mixed Methods Ethnography of a Digital Library

Simon François Dumas Primbault

At the crossroads of the ethnography of scholarly practices and digital humanities, this study proposes to consider the exploratory aspect of the scientific activity as an intellectual path through a corpus made accessible by an online platform. My case st ...

2022

Science on the Summit: Exploring Scientific Tourism Through the Lens of Eighteenth Century Mountain Ascents

Jérôme Baudry, Ion-Gabriel Mihailescu, Simon François Dumas Primbault

This contribution argues that a particular scientific context made summits a place of interest for eighteenth-century travelers. This development is connected to two particular scientific practices. First, the challenges raised by making the barometer into ...

2022

A minimalistic cyclic ice-binding peptide from phage display

Harm-Anton Klok, Luciano Andres Abriata, Corey Alfred Stevens, Matthew Gibson, Xudong Kong

Developing molecules that emulate the properties of naturally occurring ice-binding proteins (IBPs) is a daunting challenge. Rather than relying on the (limited) existing structure–property relationships that have been established for IBPs, here we report ...

2021

Cross-validation is commonly used to select the recommendation algorithms that will generalize best on yet unknown data. Yet, in many situations the available dataset used for cross-validation is scarce and the selected algorithm might not be the best suit ...

Springer2021