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The objective of molecular electron microscopy (EM) is to use etectron microscopes to visualize the structure of biological molecules. This Review provides a brief overview of the methods used in molecular EM, their respective strengths and successes, and ...
The core–shell structure of a range of acrylic–acrylic latexes has been investigated by combining different specimen preparation methods with transmission electron microscopy (TEM), dark-field scanning transmission electron microscopy (DSTEM) and low-volta ...
The core–shell structure of a range of acrylic–acrylic latexes has been investigated by combining different specimen preparation methods with transmission electron microscopy (TEM), dark-field scanning transmission electron microscopy (DSTEM) and low-volta ...
The third and most recently identified Parkinson's disease-linked variant of the neuronal protein alpha-synuclein to be identified (E46K) results in widespread brain pathology and early onset Parkinson symptoms (Zarranz et al. (2004) Ann. Neurol. 55, 164-1 ...
The fabrication of gold Fresnel zone plates, by a combination of e-beam lithography and electrodeposition, with a 30 nm outermost zone width and a 450 nm-thick structure is described. The e-beam lithography process was implemented with a careful evaluation ...
Self-assembly in the bulk of a series of hybrid triblock copolymers formed by a poly(9,9-dihexylfluorene-2,7-diyl) (PHF) middle block and two poly(gamma-benzyl-L-glutamate) (PBLG) end blocks has been studied. Since the alpha-helical secondary structure of ...
structural defects induced by He implantation in GaN epilayer at high fluence (1 X 10(17) He/cm(2)) and elevated temperature (750 degrees C) have been studied by conventional and high resolution transmission electron microscopy. In addition to the planar i ...
The investigation of two hexa-peri-hexabenzocoronene (HBC) derivatives carrying linear or branched perfluoroalkylated side chains is reported. Polycondensed aromatic hydrocarbons (PAH) such as HBC derivatives are well known to self-organize to form highly ...
Microvilli are found on the surface of many cell types, including the mammalian oocyte, where they are thought to act in initial contact of sperm and oocyte plasma membranes. CD9 is currently the only oocyte protein known to be required for sperm-oocyte fu ...
In this paper, we describe two methods for computerized analysis of cryo electron tomography reconstructions of biomolecules. Both methods aim at quantifying the degree of structural flexibility of macromolecules and eventually resolving the inner dynamics ...