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Different responses of mice and rats hippocampus CA1 pyramidal neurons to in vitro and in vivo-like inputs

Related publications (42)

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Neurons process information through spatiotemporal integration of synaptic input. Synaptic transmission between any given pair of neurons is typically a dynamic process with presynaptic action potentials (APs) evoking depressing or facilitating postsynapti ...

Oxford Univ Press Inc2017

Cell-type- and activity-dependent extracellular correlates of intracellular spiking

Henry Markram, Rodrigo de Campos Perin, Constantinos Anastassiou

Despite decades of extracellular action potential (EAP) recordings monitoring brain activity, the biophysical origin and inherent variability of these signals remains enigmatic. We performed whole-cell patch recordings of excitatory and inhibitory neurons ...

American Physiological Society2015

Delayed and Temporally Imprecise Neurotransmission in Reorganizing Cortical Microcircuits

Graham Knott, Anne Alison Jorstad, Yuan Liu, Yan Liu

Synaptic neurotransmission is modified at cortical connections throughout life. Varying the amplitude of the postsynaptic response is one mechanism that generates flexible signaling in neural circuits. The timing of the synaptic response may also play a ro ...

Soc Neuroscience2015

Motor Control in the Mouse Whisker System

Varun Sreenivasan

The motor systems of the mammalian brain are a remarkable product of many millions of years of evolution. It is the motor systems that make us and other mammals mobile, that guide our actions in response to sensory information and conversely modulate the v ...

EPFL2015

Neuronal firing, synaptic transmission, and its plasticity form the building blocks for processing and storage of information in the brain. It is unknown whether adult human synapses are more efficient in transferring information between neurons than roden ...

Public Library Science2014

The neocortex is the most distinctive feature of the mammalian brain and it is considered to be the substrate of high-order cognitive functions. The nature and the arrangement of the diverse neuronal elements constituting its multiple areas have received l ...

EPFL2014

Dynamics of self-sustained asynchronous-irregular activity in random networks of spiking neurons with strong synapses

Marc-Oliver Gewaltig

Random networks of integrate-and-fire neurons with strong current-based synapse scan, unlike previously believed, assume stable states of sustained asynchronous and irregular firing, even without external random background or pacemaker neurons. We analyze ...

Frontiers Research Foundation2014

Improved methodology and set-point design for diagnosis of model-plant mismatch in control loops using plant-model ratio

Alireza Karimi

Performance of any model-based control scheme depends on the quality of model. When these schemes deliver poor loop performance due to model-plant mismatch (MPM), a detection of the same needs to be in place. A recently introduced plant model ratio (PMR) n ...

Elsevier2014

The Green's function formalism as a bridge between single- and multi-compartmental modeling

Willem Anna Mark Wybo, Benjamin Torben-Nielsen

Neurons are spatially extended structures that receive and process inputs on their dendrites. It is generally accepted that neuronal computations arise from the active integration of synaptic inputs along a dendrite between the input location and the locat ...

Springer Berlin Heidelberg2013

Identifying the structure and dynamics of synaptic interactions between neurons is the first step to understanding neural network dynamics. The presence of synaptic connections is traditionally inferred through the use of targeted stimulation and paired re ...

Public Library of Science2013