Publication
Successful MRI-Guided Focused Ultrasound Thalamotomy after Ipsilateral Gamma Knife Radiosurgery for Essential Tremor: A Case Report with Video
Related publications (12)
Normalization of aberrant pretherapeutic dynamic functional connectivity of extrastriate visual system in patients who underwent thalamotomy with stereotactic radiosurgery for essential tremor: a resting-state functional MRI study
Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Constantin Tuleasca, Thomas William Arthur Bolton, Elena Najdenovska
OBJECTIVE The tremor circuitry has commonly been hypothesized to be driven by one or multiple pacemakers within the cerebello-thalamo-cortical pathway, including the cerebellum, contralateral motor thalamus, and primary motor cortex. However, previous stud ...
2020Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor
Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Constantin Tuleasca, Thomas William Arthur Bolton, Elena Najdenovska
OBJECTIVE Essential tremor (ET) is the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic deep brain stimulation or radiofrequency thalamotomy or, alternatively, minimally invasive techniques, including stereotactic rad ...
AMER ASSOC NEUROLOGICAL SURGEONS2018System Design and Advanced Circuit Techniques for Bi-Directional Brain-Machine Interfaces
Bi-directional brain-machine interfaces (BBMIs) that can capture electrophysiological signals and provide feedback through electrical stimulation are emerging tools with various applica-tions in fundamental neuroscience research as well as in clinical trea ...
EPFL2018Exploring the pathological interaction between LRRK2 and alpha-synuclein
Parkinson’s disease (PD) is the most common age-related neurodegenerative movement disorder that affects 1-2% of the general population over the age of 65 and rising to 4-5% over 80 years of age. It is estimated that 6.3 million people worldwide have Parki ...
EPFL2014Wireless Power Transfer and Data Communication for Intracranial Neural Implants Case Study
Recording neural activities plays an important role in numerous applications ranging from brain mapping to implementation of brain-machine interfaces (BMI) to recover lost functions or to understand the mechanisms behind the neurological disorders such as ...
EPFL2014A NEW APPROACH FOR CEREBELLO-THALAMIC MOTOR NETWORK EVALUATION IN ASYMPTOMATIC PREMUTATION CARRIERS AT RISK FOR FXTAS
Meritxell Bach Cuadra, Elena Najdenovska, Naghmeh Ghazaleh
Fragile-X tremor/ataxia syndrome (FXTAS) is a late onset movement disorder affecting FMR1 premutation carriers. In our recent work (Battistella et al., 2013, ) we demonstrated a unique pattern of preclinical changes in young asymptomatic carriers involving ...
2013Effect of realistic modeling of deep brain stimulation on the prediction of volume of active tissue
Juan Ramon Mosig, Laleh Golestanirad
Deep brain stimulation (DBS) is a well-established treatment for Parkinson's disease, essential tremor and dystonia. It has also been successfully applied to treat various other neurological and psychiatric conditions including depression and obsessive-com ...
2012High intensity focused ultrasound for transcranial therapy of brain lesions and disorders
Yves Martin, Najat Salameh, Benjamin Robert
A novel MR-guided brain therapy device operating at 1 MHz has been designed and constructed. The system has been installed and tested in a clinical 1.5 T Philips Achieva MRI. Skull bone distortions induced on the ultrasonic beam are corrected using the con ...
2010Quantification of tremor and bradykinesia in Parkinson’s disease using a novel ambulatory monitoring system
Kamiar Aminian, Arash Salarian
An ambulatory system for quantification of tremor and bradykinesia in patients with Parkinson's disease (PD) is presented. To record movements of the upper extremities, a sensing units which included miniature gyroscopes, has been fixed to each of the fore ...
2007A Cross Validation Study of Deep Brain Stimulation Targeting: From Experts to Atlas-Based, Segmentation-Based and Automatic Registration Algorithms
Jean-Philippe Thiran, Meritxell Bach Cuadra, Reto Meuli, Olivier Cuisenaire, Francisco Javier Sanchez Castro
Validation of image registration algorithms is a difficult task and open-ended problem, usually application-dependent. In this paper we focus on deep brain stimulation (DBS) targeting for the treatment of movement disorders like Parkinson's disease and ess ...
2006