Towards improving full-length ribosome density prediction by bridging sequence and graph-based representations
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The interconversion of two secondary structure types (alpha-helix reversible beta-sheet) induced by external conditions such as pH, temperature, concentration, and solvent could be proved in a new class of amphiphilic peptides (switch peptides) in aqueous ...
1991
A detailed characterization of the time scales and mechanisms by which RNA molecules change their folding structure upon binding of metabolites or during catalysis is important for the understanding of the different biological functions of RNA. The folding ...
EPFL2006
Rotationally resolved spectra in the 5 nu (1) region of (CH3OH)-C-13 reveal strong vibrational splittings, which by analogy to (CH3OH)-C-12, we assign to a resonance between 5 nu (1) and 4 nu (1)+nu (2). Accordingly, the vibrational dynamics on a subpicose ...
2000
Proteolytic activation, oligomerization, and membrane insertion are three steps that precede channel formation by the bacterial toxin aerolysin. Using attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and hydrogen-deuterium exc ...
1997
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was isolated. The cDNA-deduced amino acid sequence revealed a putativ ...
1992
A report from a symposium on the prepn. and conformation of template assembled synthetic proteins, consisting of lysine-contg. cyclic decapeptide with four helical peptides attached via the lysine e-amino groups. Conformational studies show a clear templat ...
1991
The retention behaviour of a six-helix bundle template-assembled synthetic protein (TASP) molecule and its amphiphilic building blocks was investigated. The TASP consists of a circular template, cyclo(1-12)[KG]6, and six identical potentially alpha-helical ...
1991
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The reversible, oriented immobilization of proteins on solid surfaces is a prerequisite for the investigation of mol. interactions and the controlled formation of supramol. assemblies. This paper describes a generally applicable method using a synthetic ch ...
1999
Cross-correlation between the fluctuations of 13Ca-Ha interactions affects the relaxation behavior of two-spin coherences (zero- and double-quantum coherences) involving the 13Ca nuclei of two successive amino acid residues. The cross-correlation rates are ...
2000
Telomerase is composed of protein and RNA. The RNA serves as a template for telomere DNA synthesis and may also be important for enzyme structure or catalysis. We have used the presence of conserved sequence elements in the promoter and template regions to ...
