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The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation

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The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation

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Phosphorylation of α-synuclein is crucial in compensating for proteasomal dysfunction

Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

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Visualization of proteins in intact cells with a clonable tag for electron microscopy

Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy