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Variability is the rule: Neurophysiology and contextual visual processing in schizophrenia

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EEG microstates in schizophrenia: a candidate endophenotype

Michael Herzog, Christine Mohr, Maya Roinishvili, Ophélie Gladys Favrod, Patricia Figueiredo

Objective: Electroencephalogram (EEG) microstates are on-going scalp potential configurations that remain stable for around 80 ms. Abnormal temporal dynamics of specific classes of microstates have been suggested as a potential endophenotype for schizophre ...

2019

A Multifaceted Approach to Covert Attention Brain-Computer Interfaces

Christoph Schneider

Over the last years, brain-computer interfaces (BCIs) have shown their value for assistive technology and neurorehabilitation. Recently, a BCI-approach for the rehabilitation of hemispatial neglect has been proposed on the basis of covert visuospatial atte ...

EPFL2018

Visual backward masking in siblings of schizophrenia patients: evidence for a compensation mechanism

Michael Herzog, Maya Roinishvili, Patricia Figueiredo

Visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia. Masking deficits are highly correlated with reduced EEG amplitudes. In VBM, a target stimulus is followed by a mask, which decreases performance on the target. Here, we inves ...

2017

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Schizophrenia is a heterogeneous disease strongly influenced by genetic factors. We have previously shown that visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia (Chkonia et al., 2010). Importantly, not only patients but also ...

2017

Neural correlates of visual backward masking in psychosis

Michael Herzog, Christine Mohr, Maya Roinishvili, Ophélie Gladys Favrod

In visual backward masking (VBM), a target is followed by a mask, which deteriorates performance on the target. Schizophrenia and first episodes patients show strong behavioral deficits, reflected in strongly reduced amplitudes of the EEG as compared to co ...

2017

Simultaneous EEG-fMRI at ultra-high field for the study of human brain function

João Pedro Forjaco Jorge

Scalp electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have highly complementary domains, and their combination has been actively sought within neuroscience research. The important gains in fMRI sensitivity achieved with higher ...

EPFL2016

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Despite technical advances in brain machine interfaces (BMI), for as-yet unknown reasons the ability to control a BMI remains limited to a subset of users. We investigate whether individual differences in BMI control based on motor imagery (MI) are related ...

2016

The complexity of schizophrenia: a battery of tests

Michael Herzog

Schizophrenia research has focused on single mechanisms mainly. Classically, a paradigm is chosen, such as a cognitive or perceptual test. The outcome is usually that schizophrenia patients perform worse than controls. Substantial research is then spent to ...

2016

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Schizophrenia is a heterogeneous disorder and among other symptoms, patients have important visual impairments. Visual paradigms are therefore important tools to investigate the mechanisms of schizophrenia. During the last period of the NCCR, we have chara ...

2015

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Endophenotypes are of crucial interest for schizophrenia research linking genetic abnormalities to pathology. During the last NCCR period, we have characterized one endophenotype, based on visual backward masking deficits, behaviourally and genetically (po ...

2014