Effective minimal threshold models of neuronal activity
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The brain is the most mysterious and intricate biological structure known to man. It dominates the way we live, think, reason and behave. It is built of billions of neurons that communicate with each other through trillions of connections using electrical ...
Statistical models of neural activity are integral to modern neuroscience. Recently interest has grown in modeling the spiking activity of populations of simultaneously recorded neurons to study the effects of correlations and functional connectivity on ne ...
Multiple measures have been developed to quantify the similarity between two spike trains. These measures have been used for the quantification of the mismatch between neuron models and experiments as well as for the classification of neuronal responses in ...
Predicting activity of single neuron is an important part of the computational neuroscience and a great challenge. Several mathematical models exist, from the simple (one compartment and few parameters, like the SRM or the IF-type models), to the more comp ...
The complexity of processes occurring in the brain is an intriguing issue not just for scientists and medical doctors, but the humanity in general. The cortex ability to perceive and analyze an enormous amount of information in an instance of time, the par ...
Statistical models of neural activity are at the core of the field of modern computational neuroscience. The activity of single neurons has been modeled to successfully explain dependencies of neural dynamics to its own spiking history, to external stimuli ...
In computational neuroscience, it is of crucial importance to dispose of a model that is able to accurately describe the single-neuron activity. This model should be at the same time biologically relevant and computationally fast. Many different phenomenol ...
Stochastic channel gating is the major source of intrinsic neuronal noise whose functional consequences at the microcircuit- and network-levels have been only partly explored. A systematic study of this channel noise in large ensembles of biophysically det ...
Multiple types of measures have been developed to measure the similarity between two spike trains. These were extensively used to classify neuron responses according to stimuli and to validate mathematical models that predict the spike times. Here we analy ...
As large-scale, detailed network modeling projects are flourishing in the field of computational neuroscience, it is more and more important to design single neuron models that not only capture qualitative features of real neurons but are quantitatively ac ...