Publication

New strategies for highly efficient medical MRI contrast agents

Related publications (168)

Quantitative Microstructural Imaging for Clinical Use

Today, Magnetic Resonance Imaging (MRI) is a well-established medical imaging modality thanks to its excellent soft tissue contrast. Conventional MR image contrasts can be weighted towards one or more physical properties that discriminate different tissues ...

EPFL2021

Vascular-targeted micelles as a specific MRI contrast agent for molecular imaging of fibrin clots and cancer cells

Anne-Sophie Chauvin, Aurélien Thomas, Vassily Vorobiev

Molecular medical imaging is intended to increase the accuracy of diagnosis, particularly in cardiovascular and cancer-related diseases, where early detection could significantly increase the treatment success rate. In this study, we present mixed micelles ...

ELSEVIER2021

Scaling analyses for hyperpolarization transfer across a spin-diffusion barrier and into bulk solid media

David Lyndon Emsley, Arthur César Pinon, Bradley Floyd Chmelka

By analogy to heat and mass transfer film theory, a general approach is introduced for determining hyperpolarization transfer rates between dilute electron spins and a surrounding nuclear ensemble. These analyses provide new quantitative relationships for ...

ROYAL SOC CHEMISTRY2021

Core-Valence Attosecond Transient Absorption Spectroscopy of Polyatomic Molecules

Jiri Vanicek, Nikolay Golubev

Tracing ultrafast processes induced by interaction of light with matter is often very challenging. In molecular systems, the initially created electronic coherence becomes damped by the slow nuclear rearrangement on a femtosecond timescale which makes real ...

2021

Simultaneous 3D acquisition of H-1 MRF and Na-23 MRI

Tom Hilbert

Purpose To develop a 3D MR technique to simultaneously acquire proton multiparametric maps (T-1, T-2, and proton density) and sodium density weighted images over the whole brain. Methods We implemented a 3D stack-of-stars MR pulse sequence which consists o ...

WILEY2021

Metabolic contrast agents produced from transported solid C-13-glucose hyperpolarized via dynamic nuclear polarization

Andrea Capozzi, Arthur César Pinon

Magnetic Resonance Imaging combined with hyperpolarized C-13-labelled metabolic contrast agents produced via dissolution Dynamic Nuclear Polarization can, non-invasively and in real-time, report on tissue specific aberrant metabolism. However, hyperpolariz ...

NATURE RESEARCH2021

HP agents and biochemical interactions

Hikari Ananda Infinity Yoshihara

The intense but transient increase in nuclear magnetic resonance signal provided by dynamic nuclear polarization (DNP) has enabled a range of new applications, including rapid, minimally-invasive metabolic imaging at the second timescale. This chapter prov ...

Academic Press2021

Fat navigators based retrospective motion correction strategies for brain magnetic resonance imaging

Frédéric Gretsch

Magnetic resonance resonance (MRI) is a widely used modality to obtain in vivo tissue information. Clinical applications are near countless, and almost all body parts can be examined using an MR scanner. As the method is non invasive, does not use ionizing ...

EPFL2020

Nanodiamond Relaxometry-Based Detection of Free-Radical Species When Produced in Chemical Reactions in Biologically Relevant Conditions

Mayeul Sylvain Chipaux

Diamond magnetometry is a quantum sensing method involving detection of magnetic resonances with nanoscale resolution. For instance, T1 relaxation measurements, inspired by equivalent concepts in magnetic resonance imaging (MRI), provide a signal that is e ...

AMER CHEMICAL SOC2020

Contrast-Enhanced Ultrasound Quantification: From Kinetic Modeling To Machine Learning

Marcel Arditi

Ultrasound contrast agents (UCAs) have opened up immense diagnostic possibilities by combined use of indicator dilution principles and dynamic contrast-enhanced ultrasound (DCE-US) imaging. UCAs are microbubbles encapsulated in a biocompatible shell. With ...

2020

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.