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Reduced cyclic stretch, endothelial dysfunction, and oxidative stress: an ex vivo model

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Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Paolo Silacci, Tyler Nerton Thacher, Veronica Gambillara
2009

Abstract

The objective of this study was to investigate whether reduction of cyclic circumferential stretch will impair endothelial function and elevate basal levels of oxidative stress, both known risk factors linked to cardiovascular disease.

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https://infoscience.epfl.ch/entities/publication/52d24786-ebfa-431e-bce1-de35cde5d880

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Related concepts (17)

In simple terms, risk is the possibility of something bad happening. Risk involves uncertainty about the effects/implications of an activity with respect to something that humans value (such as health, well-being, wealth, property or the environment), often focusing on negative, undesirable consequences. Many different definitions have been proposed. The international standard definition of risk for common understanding in different applications is "effect of uncertainty on objectives".

Risk assessment

Risk assessment determines possible mishaps, their likelihood and consequences, and the tolerances for such events. The results of this process may be expressed in a quantitative or qualitative fashion. Risk assessment is an inherent part of a broader risk management strategy to help reduce any potential risk-related consequences. More precisely, risk assessment identifies and analyses potential (future) events that may negatively impact individuals, assets, and/or the environment (i.e. hazard analysis).

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