Publications related to Pumping of mammalian cells with a nozzle-diffuser micropump

Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes

Matteo Dal Peraro, Diane Virginie Marie Lançon, Thomas Lemmin, Christophe Bovigny

Present in bacterial and mitochondrial membranes, cardiolipins have a unique dimeric structure, which carries up to two charges (i.e., one per phosphate group) and, under physiological conditions, can be unprotonated or singly protonated. Exhaustive models ...

Amer Chemical Soc2013

Cell-Penetrating Nanoparticles

Randy Patrick Carney

For targeted cellular therapy using both synthetic and natural biomaterials, there is a need for better understanding of cell penetration mechanisms. Recently, nanoparticles (NPs) coated with mixed-ligand self-assembled monolayers exhibiting order in their ...

EPFL2013

Palmitoylation cycles and regulation of protein function (Review)

Steinunn Baekkeskov Hanahan

The efficacy and success of many cellular processes is dependent on a tight orchestration of proteins trafficking to and from their site(s) of action in a time-controlled fashion. Recently, a dynamic cycle of palmitoylation/de-palmitoylation has been shown ...

Taylor & Francis2009

Molecular View of Cholesterol Flip-Flop and Chemical Potential in Different Membrane Environments

Marlon Hinner

The relative stability of cholesterol in cellular membranes and the thermodynamics of fluctuations from equilibrium have important consequences for sterol trafficking and lateral domain formation. We used molecular dynamics computer simulations to investig ...

2009

Near-field optical probes provide subdiffraction-limited excitation areas for fluorescence correlation spectroscopy on membranes

Dusan Vobornik

Near-field optical probes have been used to produce a subdiffraction-limited ob- servation area for fluorescence correlation spectroscopy (FCS) experiments on supported membranes. The design of a bent, etched fiber probe that is compatible with biological ...

2009

Miniaturized bioanalytics to probe the function of membrane proteins

Pedro Pascoal

G-protein coupled receptors (GPCRs) are the most abundant class of proteins in the cell body. Such receptors are of major interest as potential therapeutic targets. Downscaling and parallelization of bioanalytics opens novel routes to rapidly screen and id ...

EPFL2008

Spontaneous $ Na ^{ + } $ Transients in Individual Mitochondria of Intact Astrocytes

Michaël Unser, Dimitri Nestor Alice Van De Ville, Jean-Yves Chatton

Mitochondria in intact cells maintain low

Na ^{ + }

levels despite the large electrochemical gradient favoring cation influx into the matrix. In addition, they display individual spontaneous transient depolarizations. We report here that individual mit ...

Wiley-Liss2008

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

Hui Wang

To explore the real-time dynamic behavior of molecular transporters of the cell-penetrating-peptide (CPP) type on a biological membrane, single fluorescently labeled oligoarginine conjugates were imaged interacting with the plasma membrane of Chinese hamst ...

2008

About lipids and toxins

Françoise Gisou van der Goot Grunberg

Many mono or multicellular organisms secrete soluble proteins, referred to as protein toxins, which alter the behavior of foreign, or target cells, possibly leading to their death. These toxins affect either the cell membrane by forming pores or modifying ...

2006

Micro- and nanostructured devices for investigating biomolecular interactions

Jürgen Brugger, Horst Vogel, Christian Santschi, Christophe Danelon, Jean-Baptiste Perez

Cell membrane receptors and ion channels are essential in many different cellular processes. To analyse the activity of membrane proteins in vesicles and biological cells, we fabricated micro- nanostructured chips, enabling the application of electrophysio ...

2006

Pumping of mammalian cells with a nozzle-diffuser micropump

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Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes

Cell-Penetrating Nanoparticles

Palmitoylation cycles and regulation of protein function (Review)

Molecular View of Cholesterol Flip-Flop and Chemical Potential in Different Membrane Environments

Near-field optical probes provide subdiffraction-limited excitation areas for fluorescence correlation spectroscopy on membranes

Miniaturized bioanalytics to probe the function of membrane proteins

Spontaneous $ Na ^{ + } $ Transients in Individual Mitochondria of Intact Astrocytes

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

About lipids and toxins

Micro- and nanostructured devices for investigating biomolecular interactions

Cell-Penetrating Nanoparticles

Molecular View of Cholesterol Flip-Flop and Chemical Potential in Different Membrane Environments

Micro- and nanostructured devices for investigating biomolecular interactions

Miniaturized bioanalytics to probe the function of membrane proteins

About lipids and toxins

Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes

Palmitoylation cycles and regulation of protein function (Review)

Spontaneous $ Na ^{ + } $ Transients in Individual Mitochondria of Intact Astrocytes

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

Near-field optical probes provide subdiffraction-limited excitation areas for fluorescence correlation spectroscopy on membranes