The Quest for Genes Involved in Adaptation to Climate Change in Ruminant Livestock

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Single-mitosis dissection of acute and chronic DNA mutagenesis and repair

How chronic mutational processes and punctuated bursts of DNA damage drive evolution of the cancer genome is poorly understood. Here, we demonstrate a strategy to disentangle and quantify distinct mechanisms underlying genome evolution in single cells, dur ...

Nature Portfolio2024

Genome sequences of Vibrio cholerae strains isolated in the DRC between 2009 and 2012

Melanie Blokesch, Sandrine Stutzmann, Alexandre Lemopoulos, Natalia Carolina Drebes Dorr

Vibrio cholerae has caused seven cholera pandemics in the past two centuries. The seventh and ongoing pandemic has been particularly severe on the African continent. Here, we report long read-based genome sequences of six V. cholerae strains isolated in th ...

2024

Reconstruction and analysis of genome-scale metabolic networks in single organisms and microbial communities

Evangelia Vagena

Microorganisms are a key component in the chain of life. They are essential for agriculture, produce a large proportion of oxygen, and play a central role in the cycle of elements. Microorganisms are widely used in the production of food and alcoholic beve ...

EPFL2024

Reproductive isolation arises during laboratory adaptation to a novel hot environment

Ana Marija Jaksic

Background: Reproductive isolation can result from adaptive processes (e.g., ecological speciation and mutation-order speciation) or stochastic processes such as "system drift" model. Ecological speciation predicts barriers to gene flow between populations ...

BMC2024

Toward universal cell embeddings: integrating single-cell RNA-seq datasets across species with SATURN

Maria Brbic, Ziang Li

Analysis of single-cell datasets generated from diverse organisms offers unprecedented opportunities to unravel fundamental evolutionary processes of conservation and diversification of cell types. However, interspecies genomic differences limit the joint ...

Nature Portfolio2024

Meeting our Makers: Uncovering the cis-regulatory activity of transposable elements using statistical learning

Cyril David Son-Tuyên Pulver

The adaptation of organisms to their environment depends on the innovative potential inherent to genetic variation. In complex organisms such as mammals, processes like development and immunity require tight gene regulation. Complex forms emerge more often ...

EPFL2024

Climate risk assessment of buildings: An analysis of operating emissions of commercial offices in Australia

Arianna Brambilla

Building climate risk assessment involves benchmarking a building's energy use intensity against decarbonisation pathways to mitigate the impacts on climate change. Various climate risk assessment tools and frameworks are used for commercial buildings in d ...

Elsevier Science Sa2024

Euclid preparation XXXVII. Galaxy colour selections with Euclid and ground photometry for cluster weak-lensing analyses

Frédéric Courbin, Georges Meylan, Gianluca Castignani, Maurizio Martinelli, Matthias Wiesmann, Yi Wang, Richard Massey, Fabio Finelli, Marcello Farina

Aims. We derived galaxy colour selections from Euclid and ground-based photometry, aiming to accurately define background galaxy samples in cluster weak-lensing analyses. These selections have been implemented in the Euclid data analysis pipelines for gala ...

Edp Sciences S A2024

Renaturation of urban rivers as a climate adaptation strategy Case study in Geneva, Switzerland

Sophie Lufkin, Emmanuel Rey

In a global context marked by the urgency of climate change, tangible actions towards the ecological transition are top priorities for the built environment. This paper presents the results of the “Maillages fertiles” research project, which seizes the opp ...

Wrocław University of Science and Technology Publishing House2024

Calibrating and validating the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) urban cooling model: case studies in France and the United States

Martí Bosch Padrós

Understanding the cooling service provided by vegetation in cities is important to inform urban policy and planning. However, the performance of decision-support tools estimating heat mitigation for urban greening strategies has not been evaluated systemat ...

Copernicus Gesellschaft Mbh2024

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Calibrating and validating the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) urban cooling model: case studies in France and the United States

Martí Bosch Padrós

Copernicus Gesellschaft Mbh2024