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Remote Substituent Effect on the Electrophilic Additions of 1,3-Dienes - Synthesis of (2r)-5-(Acetoxymethyl)-2-Acetyl-1,2,3,4-Tetrahydro-10-Methoxynaphthacene -2,12-Diyl Diacetate
Related publications (19)
Umpolung Of Electron-Rich Heteroarenes With Hypervalent Iodine Reagents
Five-membered heterocycles are well known for their innate nucleophilicity. In contrast, reaction of these heterocycles as electrophiles is less established and has become only recently an intensively investigated research area in synthetic chemistry. The ...
PERGAMON-ELSEVIER SCIENCE LTD2021Reactions of nitrogen-containing compounds with ozone: kinetics and mechanisms
Nitrogen-containing moieties are widespread in natural waters in dissolved organic nitrogen and micropollu-tants. They are often susceptible to an electrophilic attack of ozone because of the electron-rich nature of the neutral form of nitrogen in organic ...
EPFL2020Organocatalysts in C-N Bond Forming Reactions of Amines with CO2
The thesis describes a simple approach for N-formylation of amines with CO2 and hydrosilane reducing agents, the use of organic salts as N-formylation catalysts, their physical properties required for high catalytic activity and their role in the catalytic ...
EPFL2019Getting the Right Grip? How Understanding Electrophile Selectivity Profiles Could Illuminate Our Understanding of Redox Signaling
Recent Advances: Herein, we focus on the first step of this process, electrophile sensing. Electrophile sensing is typically a deceptively simple reaction between the thiol of a protein cysteine, of which there are around 200,000 in the human proteome, and ...
MARY ANN LIEBERT, INC2019Decarboxylative C(sp3)–N cross-coupling via synergetic photoredox and copper catalysis
Xile Hu, Runze Mao, Jonathan Balon, Adrian Frey
Amines are a quintessential moiety in bioactive molecules, pharmaceuticals and organic materials. Transition-metal-catalysed C–N coupling of aryl electrophiles has been established as a powerful and reliable method for amine synthesis. However, the analogo ...
2018Stereoselective synthesis of alkenes via base-metal-catalyzed addition reactions to alkynes and activation of hydrogen peroxide and carbon dioxide by iron complexes
Alkene functionality can be found in the majority of natural products, drugs, catalysts and organic materials. Therefore, methods of C-C double bond formation constitute a cornerstone of organic synthesis. Selective formation of either (Z)- or (E)-isomer i ...
EPFL2017Organocatalysis: Fundamentals and Comparisons to Metal and Enzyme Catalysis
Catalysis fulfills the promise that high-yielding chemical transformations will require little energy and produce no toxic waste. This message is carried by the study of the evolution of molecular catalysis of some of the most important reactions in organi ...
Mdpi Ag2016Synthesis of Alkynylated Heterocycles by Direct C-H Alkynylation or Domino Alkynylation Reactions
Heterocycles are important compounds in organic chemistry. To introduce functional groups on heterocycles or synthesize functionalized heterocycles stays a hot topic of research. Among all the functional groups, alkynes attracted a lot of attention not onl ...
EPFL2016Mild synthesis of mercaptonitriles from vinyl nitriles and their cyclization reactions
Thiol-ene addition of thioacetic acid A is widely used in the synthesis of thiols from vinyl precursors, but so far has not been conducted on non-conjugated vinyl nitriles. The challenge when vinyl nitriles are used is to selectively conduct the thiol-ene ...
Royal Soc Chemistry2016Chemical Oxidation of Dissolved Organic Matter by Chlorine Dioxide, Chlorine, And Ozone: Effects on Its Optical and Antioxidant Properties
Urs von Gunten, Silvio Canonica
In water treatment dissolved organic matter (DOM) is typically the major sink for chemical oxidants. The resulting changes in DOM, such as its optical properties have been measured to follow the oxidation processes. However, such measurements contain only ...
Amer Chemical Soc2013