Publications related to Synthesis of 4-hydroxy-2,6-bis(hydroxymethyl)tetrahydropyran-2-carbaldehyde derivatives

Directed evolution of O6-alkylguanine-DNA alkyltransferase for applications in protein labeling

Kai Johnsson, Christian Heinis, Alexandre Juillerat, Christopher Chidley, Thomas Gronemeyer

The specific reaction of O6-alkylguanine-DNA alkyltransferase (AGT) with O6-benzylguanine (BG) derivatives allows for a specific labeling of AGT fusion proteins with chemically diverse compounds in living cells and in vitro. The efficiency of the labeling ...

Oxford University Press2006

Time-lag in Derivative Convergence for Fixed Point Iterations

Daniel Kressner

In an earlier study it was proven and experimentally confirmed on a 2D Euler code that fixed point iterations can be differentiated to yield first and second order derivatives of implicit functions that are defined by state equations. It was also asserted ...

2005

Heterosubstituted or functionalized derivatives of 1- and 2-(trifluoromethyl)naphthalenes emanating from aryne adducts

Frédéric Bailly, Fabrice Cottet

More than two dozen new CF3-substituted naphthalene derivs. were prepd. in an expedient way by employing 3- and 4-(trifluoromethyl)benzyne as the key intermediates. 2- And 4-Chlorobenzotrifluoride were treated with butyllithium and the organometallic speci ...

2005

Density-functional perturbational theory for dielectric tensors in the ultrasoft pseudopotential scheme

Alfredo Pasquarello

We introduce a density-functional perturbational scheme based on ultrasoft pseudopotentials for calculating dielectric tensors of periodic systems. We obtain a variational functional for the second-order derivative of the energy with respect to an electric ...

2004

Scope and limitations of the double [4+3]-cycloadditions of 2-oxyallyl cations to 2,2 '-methylenedifuran and derivatives

Pierre Vogel, Marc-Etienne Schwenter, Kai Torsten Meilert

The reactivity of various 2-oxyallyl cations toward 2,2'-methylenedifuran (1b), 2,2'-(hydroxymethyl)difuran (1c), 2,2'-(trimethylsilylmethylene)difuran (1d), and di(2-furyl)methanone (1e) has been explored. Difuryl derivatives 1c, 1d, and le refused to und ...

2003

Fractional Wavelets, Derivatives, and Besov Spaces

Michaël Unser, Thierry Blu

We show that a multi-dimensional scaling function of order γ (possibly fractional) can always be represented as the convolution of a polyharmonic B-spline of order γ and a distribution with a bounded Fourier transform which has neither order nor smoothness ...

SPIE2003

$ l _{ p } $ -Multiresolution Analysis: How to Reduce Ringing and Sparsify the Error

Michaël Unser, Thierry Blu

We propose to design the reduction operator of an image pyramid so as to minimize the approximation error in the

l _{ p }

-sense (not restricted to the usual p=2), where p can take non-integer values. The underlying image model is specified using shift- ...

IEEE2002

Asymmetric synthesis of 1-aminopentadecane-3,5,7,9,11,13,15-heptols and of 1,15-diaminopentadecane-3,5,7,9,11,13-hexols and derivatives

Pierre Vogel, Sandrine Gerber

Starting from 2,2'-methylenedifuran, enantiomerically enriched (98%) (3R,5S,7R,9S,11R,13R)- and (3R,5S,7S,9R,11R,13R)-15-amino-5,7,9,11-tetrahydroxy-3,13-bis(4-methoxyb enzoyloxy)pentadec-1-yl) pivalate were prepared as well as (3R,5R,7R,9R,11S,13S)-1,15-d ...

2002

Derivatives of (2R,3R,4S)-2-Aminomethylpyrrolidine-3,4-diol are Selective alpha-Mannosidase Inhibitors

Pierre Vogel, Sandrine Gerber, Inmaculada Robina, Eliazar Rodriguez Garcia, Raynald Demange

A collection of (2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl derivatives have been tested for their inhibitory activities toward 25 glycosidases. Competitive (K-i=7.4 VM) and selective inhibition of alpha -mannosidase from jack bean has been found for (2R,3R,4S ...

2001

Using Multiple Time Scales in the Framework of Multi-Stream Speech Recognition

Hervé Bourlard, Astrid Hagen

In this paper, we present a new approach to incorporating multiple time scale information as independent streams in multi-stream processing. To illustrate the procedure, we take two different sets of multiple time scale features. In the first system, these ...

IDIAP2000

Synthesis of 4-hydroxy-2,6-bis(hydroxymethyl)tetrahydropyran-2-carbaldehyde derivatives

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Directed evolution of O6-alkylguanine-DNA alkyltransferase for applications in protein labeling

Time-lag in Derivative Convergence for Fixed Point Iterations

Heterosubstituted or functionalized derivatives of 1- and 2-(trifluoromethyl)naphthalenes emanating from aryne adducts

Density-functional perturbational theory for dielectric tensors in the ultrasoft pseudopotential scheme

Scope and limitations of the double [4+3]-cycloadditions of 2-oxyallyl cations to 2,2 '-methylenedifuran and derivatives

Fractional Wavelets, Derivatives, and Besov Spaces

$ l _{ p } $ -Multiresolution Analysis: How to Reduce Ringing and Sparsify the Error

Asymmetric synthesis of 1-aminopentadecane-3,5,7,9,11,13,15-heptols and of 1,15-diaminopentadecane-3,5,7,9,11,13-hexols and derivatives

Derivatives of (2R,3R,4S)-2-Aminomethylpyrrolidine-3,4-diol are Selective alpha-Mannosidase Inhibitors

Using Multiple Time Scales in the Framework of Multi-Stream Speech Recognition

Directed evolution of O6-alkylguanine-DNA alkyltransferase for applications in protein labeling

Density-functional perturbational theory for dielectric tensors in the ultrasoft pseudopotential scheme

Time-lag in Derivative Convergence for Fixed Point Iterations

Fractional Wavelets, Derivatives, and Besov Spaces

$ l _{ p } $ -Multiresolution Analysis: How to Reduce Ringing and Sparsify the Error

Asymmetric synthesis of 1-aminopentadecane-3,5,7,9,11,13,15-heptols and of 1,15-diaminopentadecane-3,5,7,9,11,13-hexols and derivatives

Heterosubstituted or functionalized derivatives of 1- and 2-(trifluoromethyl)naphthalenes emanating from aryne adducts

Using Multiple Time Scales in the Framework of Multi-Stream Speech Recognition

Derivatives of (2R,3R,4S)-2-Aminomethylpyrrolidine-3,4-diol are Selective alpha-Mannosidase Inhibitors

Scope and limitations of the double [4+3]-cycloadditions of 2-oxyallyl cations to 2,2 '-methylenedifuran and derivatives