The main aim of this work is to detect metabolites in the brain by means of nuclear magnetic resonance spectroscopy. We were mostly interested by glutathione (GSH) and more particularly by its cysteine part which forms a strongly coupled ABX spins system. ...
The research of this doctoral thesis was dedicated to polyelectrolytes, specifically to hydrogel materials, which result from coacervation and polyelectrolyte complex formation and have a potential as immunoprotection systems. In particular, microspheres o ...
This chapter describes the potential use of viral-mediated gene transfer in the central nervous system as a new strategy in developing animal models of neurodegenerative diseases. To illustrate the approach, procedures for the production of lentiviral vect ...
In this thesis, a new method has been developed, which determines the optical coefficients spectra (absorption and scattering) of small volumes of tissue (1 mm3) by the measurement of spatially resolved reflectance between 480 and 950 nm. Firstly, an algor ...