Long Term Hippocampal and Cortical Changes Induced by Maternal Deprivation and Neonatal Leptin Treatment in Male and Female Rats

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A dynamic attractor network model of memory formation, reinforcement and forgetting

Wulfram Gerstner, Chiara Gastaldi, Marta Boscaglia

Empirical evidence shows that memories that are frequently revisited are easy to recall, and that familiar items involve larger hippocampal representations than less familiar ones. In line with these observations, here we develop a modelling approach to pr ...

Public Library Science2023

Emotional sounds in space: asymmetrical representation within early-stage auditory areas

Stephanie Clarke

Evidence from behavioral studies suggests that the spatial origin of sounds may influence the perception of emotional valence. Using 7T fMRI we have investigated the impact of the categories of sound (vocalizations; non-vocalizations), emotional valence (p ...

FRONTIERS MEDIA SA2023

Digital reconstruction of the mammalian spinal cord: from anatomical reference volume to cell type atlas of the mouse spinal cord

Ihor Kuras

The spinal cord is an elongated nervous structure that together with the brain forms the central nervous system. It relays sensory and motor information between the brain and the body, thus controlling most somatic and autonomic body functions. In recent y ...

EPFL2023

Face your fears: attenuating remote fear memories by reconsolidation-updating

Johannes Gräff, Bianca Ambrogina Silva

Traumatic events generate some of the most enduring memories, yet little is known about how long-lasting fear memories can be attenuated. In this review, we collect the surprisingly sparse evidence on remote fear memory attenuation from both animal and hum ...

ELSEVIER SCIENCE LONDON2023

Me, Myself, and I: Neural Activity for Self versus Other across Development

Solange Noémie Jeanne Denervaud, Paola Zanchi

Although adults and children differ in self-vs.-other perception, a developmental perspective on this discriminative ability at the brain level is missing. This study examined neural activation for self-vs.-other in a sample of 39 participants spanning fou ...

MDPI2023

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Jessie Julie Mosso

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

EPFL2023

Early motor skill acquisition in healthy older adults: brain correlates of the learning process

Friedhelm Christoph Hummel, Takuya Morishita, Pablo Maceira Elvira, Manon Chloé Durand-Ruel, Chang-Hyun Park, Maeva Moyne

Motor skill learning is a crucial process at all ages. However, healthy aging is often accompanied by a reduction in motor learning capabilities. This study characterized the brain dynamics of healthy older adults during motor skill acquisition and identif ...

OXFORD UNIV PRESS INC2023

Modeling and simulation of neocortical micro- and mesocircuitry. Part II: Physiology and experimentation

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, James Gonzalo King, Rajnish Ranjan, Armando Romani, Mustafa Anil Tuncel, Aleksandra Zuzanna Teska, Polina Litvak

Cortical dynamics underlie many cognitive processes and emerge from complex multi-scale interactions, which are challenging to study in vivo. Large-scale, biophysically detailed models offer a tool which can complement laboratory approaches. We present a m ...

2024

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A dynamic attractor network model of memory formation, reinforcement and forgetting

Wulfram Gerstner, Chiara Gastaldi, Marta Boscaglia

Public Library Science2023

Emotional sounds in space: asymmetrical representation within early-stage auditory areas

Stephanie Clarke

FRONTIERS MEDIA SA2023

Digital reconstruction of the mammalian spinal cord: from anatomical reference volume to cell type atlas of the mouse spinal cord

Ihor Kuras

EPFL2023