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Thalamic control of cortical states

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Carl Petersen, Sylvain Crochet, James Poulet
2012

Abstract

We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. We demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, which can also be mimicked by optogenetic stimulation of the thalamus. The thalamus therefore is key in controlling cortical states.

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https://infoscience.epfl.ch/entities/publication/6293d4e7-0c8a-4564-840c-28d6bd9f015b

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