Publications related to DprE1-from the Discovery to the Promising Tuberculosis Drug Target

Cyclic Peptides for Drug Development

Christian Heinis, Xinjian Ji, Alexander Lund Nielsen

Cyclic peptides are fascinating molecules abundantly found in nature and exploited as molecular format for drug development as well as other applications, ranging from research tools to food additives. Advances in peptide technologies made over many years ...

Wiley-VCH Verlag GmbH2024

Fungal mycelia: From innovative materials to promising products: Insights and challenges

Wenjing Sun

In transitioning toward a sustainable economy, mycelial materials are recognized for their adaptability, biocompatibility, and eco-friendliness. This paper updates the exploration of mycelial materials, defining their scope and emphasizing the need for pre ...

Aip Publishing2024

Geospatial Tools and Remote Sensing Strategies for Timely Humanitarian Response: A Case Study on Drought Monitoring in Eswatini

Jérôme Chenal

This article explores the escalating impact of natural disasters, particularly droughts, in the Southern African Development Community (SADC), with a specific focus on Eswatini. Over the last century, approximately 63 million people in SADC countries have ...

MDPI2024

Impact of substrate clogging on vertical connectivity

Giovanni De Cesare, Romain Maxime Dubuis, Robin Schroff

Connectivity between the hyporheic zone and the flow is essential for the development of benthos and the reproductive success of spawning fish. The infiltration of fine sediment leads to clogging of the riverbed, reducing porosity and vertical water exchan ...

2023

Swiss dams: Overview of historical development

Anton Schleiss

With more than 220 large dams in operation, compared to its surface of some 41ʹ000 km2, Switzerland has a very large fleet. They were erected to meet various economic and protection needs. Their main assignments concern the storage of water for later use, ...

CRC Press/Balkema2023

The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma

Paul Joseph Dyson, Irina Sinenko, Roland Christopher Turnell-Ritson

Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the improv ...

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2023

Determinants of urban environmental quality in Morocco: The roles of energy consumption, urbanization, manufacturing, and financial development in SDG 13

Jérôme Chenal, Hassan Radoine

Studies on urban environmental quality are evolving emphasizing the need for policy response concerning the enactment of environmental regulations to attain sustainable development goals (SDGs), mainly target 13. Over the years, the concerns to improve urb ...

FRONTIERS MEDIA SA2023

Advances in hydration and thermodynamics of cementitious systems

Karen Scrivener, Patrick Juilland, Aslam Kunhi Mohamed, Fabien Jacques Michel Georget, Thomas Matschei

Optimising the hydration of cementitious materials is crucial to leverage their full potential and avoid wasting resources, embodied energy and CO2. Understanding the fundamental mechanisms is key to reach these objectives. In this paper, we review progres ...

Pergamon-Elsevier Science Ltd2023

On the development of multi-physics tools for nuclear reactor analysis based on OpenFOAM (R): state of the art, lessons learned and perspectives

Carlo Fiorina

In the last two decades, the use of OpenFOAM as a multi-physics library for nuclear applications has grown from a sporadic use for exploratory studies to a widespread application for the analysis of innovative reactor concepts and highly complex problems. ...

ELSEVIER SCIENCE SA2022

UAV in the advent of the twenties: Where we stand and what is next

Jan Skaloud, Davide Antonio Cucci

The use of Unmanned Aerial Vehicles (UAVs) has surged in the last two decades, making them popular instruments for a wide range of applications, and leading to a remarkable number of scientific contributions in geoscience, remote sensing and engineering. H ...

2022