In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

About
Privacy
Disclaimer

Graph Chatbot

Related publications (30)

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling

Wearable biosensors and smartphone applications can measure physiological variables over multiple days in free-living conditions. We measure food and drink ingestion, glucose dynamics, physical activity, heart rate (HR), and heart rate variability (HRV) in ...

CELL PRESS2023

Statistical physics of periodic biological processes

Lorenzo Talamanca

Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet. Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuat ...

EPFL2023

Data and code associated with the paper 'Mode-Specific Coupling of Nanoparticle-on-Mirror Cavities with Cylindrical Vector Beams'

Christophe Marcel Georges Galland, Valeria Vento, Sachin Suresh Verlekar, Philippe Andreas Rölli

Data and code associated with the following paper: V. Vento et al, Nano Lett. 2023 A thorough explanation of the experiment performed is available there. The name of each sub-folder and file in Maps_data_code.zip indicates the correspondin ...

Zenodo2023

ALMOST SURE SCATTERING OF THE ENERGY-CRITICAL NLS IN d > 6

Katie Sabrina Catherine Rosie Marsden

We study the energy-critical nonlinear Schrodinger equation with randomised initial data in dimensions d > 6. We prove that the Cauchy problem is almost surely globally well-posed with scattering for randomised supercritical initial data in H-s(Rd) wheneve ...

Amer Inst Mathematical Sciences-Aims2023

Data and Workflow to: Three-dimensional buoyant hydraulic fractures: finite volume release (Möri and Lecampion, (2023))

Brice Tanguy Alphonse Lecampion, Andreas Möri

This upload contains the relevant scripts, notebooks, and datasets to reproduce the numerically obtained results of the Journal article "Three-dimensional buoyant hydraulic fractures: finite volume release" by Möri and Lecampion, (2023). ...

Zenodo2023

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Martinus Gijs, Raphaël Etienne Jean Trouillon, Martin Rainer Wohlwend

Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used fixed and live-cell imaging to study microtubule-based ...

eLIFE SCIENCES PUBL LTD2023

Validating functional redundancy with mixed generative adversarial networks

Thanh Trung Huynh, Quoc Viet Hung Nguyen, Thành Tâm Nguyên, Trung-Dung Hoang

Data redundancy has been one of the most important problems in data-intensive applications such as data mining and machine learning. Removing data redundancy brings many benefits in efficient data updating, effective data storage, and error-free query proc ...

ELSEVIER2023

The circadian clock time tunes axonal regeneration

Thomas Haynes Hutson

Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and-independent mechanisms have provided important insight into neuronal regeneration, however, common denominators underpinning regeneration remain ...

Cell Press2023

Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans

Felix Naef, Cédric Gobet, Lorenzo Talamanca

The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data from the Genotype-Tissue Expression (GTEx) project with an a ...

American Association for the Advancement of Science2023

Imaging radial distribution functions of complex particles by relayed dynamic nuclear polarization

David Lyndon Emsley, Arthur César Pinon, Pierrick Berruyer

Raw data and Matlab scripts from the publication at https://doi.org/10.1021/jacs.3c01279 All codes are provided free of charge and come with no warranty. Future use (original or modified) is required to cite: Zenedo data deposit at DOI 10.5281/zenodo. ...

Zenodo2023

Page 3 of 3

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling

Felix Naef, Nicholas Edward Phillips

CELL PRESS2023

Data and code associated with the paper 'Mode-Specific Coupling of Nanoparticle-on-Mirror Cavities with Cylindrical Vector Beams'

Christophe Marcel Georges Galland, Valeria Vento, Sachin Suresh Verlekar, Philippe Andreas Rölli

Zenodo2023

Imaging radial distribution functions of complex particles by relayed dynamic nuclear polarization

David Lyndon Emsley, Arthur César Pinon, Pierrick Berruyer

Zenodo2023