Tumor necrosis factorTumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha or TNF-α) is an adipokine and a cytokine. TNF is a member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain. As an adipokine, TNF promotes insulin resistance, and is associated with obesity-induced type 2 diabetes. As a cytokine, TNF is used by the immune system for cell signaling. If macrophages (certain white blood cells) detect an infection, they release TNF to alert other immune system cells as part of an inflammatory response.
Operation (mathematics)In mathematics, an operation is a function which takes zero or more input values (also called "operands" or "arguments") to a well-defined output value. The number of operands is the arity of the operation. The most commonly studied operations are binary operations (i.e., operations of arity 2), such as addition and multiplication, and unary operations (i.e., operations of arity 1), such as additive inverse and multiplicative inverse. An operation of arity zero, or nullary operation, is a constant.
Stem cellIn multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type.
