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Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

Related publications (26)

3D printed fiber-optic nanomechanical bioprobe

Sandor Kasas, Jiangtao Zhou, Yiping Wang, Yuguang Chen

Ultrasensitive nanomechanical instruments, e.g. atomic force microscopy (AFM), can be used to perform delicate biomechanical measurements and reveal the complex mechanical environment of biological processes. However, these instruments are limited because ...

IOP Publishing Ltd2023

Exploring Novel Modalities for Optical Diffraction Tomography

Amirhossein Saba Shirvan

In the past decade, optical diffraction tomography has gained a lot of attention for its ability to create label-free three-dimensional (3D) images of the refractive index distribution of biological samples using scattered fields measured through holograph ...

EPFL2023

Cortico-muscular connectivity is modulated by passive and active Lokomat-assisted Gait

Silvestro Micera, Fiorenzo Artoni

The effects of robotic-assisted gait (RAG) training, besides conventional therapy, on neuroplasticity mechanisms and cortical integration in locomotion are still uncertain. To advance our knowledge on the matter, we determined the involvement of motor cort ...

Nature Portfolio2023

Novel Design and Implementation of a Neuromuscular Controller on a Hip Exoskeleton for Partial Gait Assistance

Auke Ijspeert, Mohamed Bouri, Ali Reza Manzoori, Andrea Di Russo, Sara Messara

Exoskeletons intended for partial assistance of walking should be able to follow the gait pattern of their users, via online adaptive control strategies rather than imposing predefined kinetic or kinematic profiles. NeuroMuscular Controllers (NMCs) are ada ...

2023

lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

Alfio Quarteroni, Francesco Regazzoni, Stefano Pagani, Marco Fedele

Background: Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-performance computational tools. Despite the dedicated endeavors ...

BMC2023

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

Alfio Quarteroni, Luca Dede'

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory system. Our mod ...

Wiley2023

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Alessia De Masi

The natural compound Cyclo Histidine-Proline (CHP) was initially discovered in the brain, but thereafter evaluated in the context of diabetes because of its hypoglycemic action. The pharmacokinetics and the toxicological profile of CHP showed it can be dos ...

EPFL2023

Improving hand prosthesis control with advanced single-finger proportional decoding and robotic shared control

Vincent Alexandre Mendez

Myoelectric prostheses allow users to recover lost functionality by controlling a robotic device with their remaining muscle activity. Commercial devices usually use a two-recording-channel system placed on specific muscles to control a single degree of fr ...

EPFL2023

Brain-controlled spinal cord stimulation to restore mobility after spinal cord injury

Carmina Andrea Galvez Solano

Spinal Cord Injury (SCI) affects almost 500,000 people every year, causing complete paralysis of both legs in severe cases, with no current treatment perspective. However, new neuroengineering technologies, such as the Brain Spine Interface (BSI), have eme ...

EPFL2023

Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

3D printed fiber-optic nanomechanical bioprobe

Exploring Novel Modalities for Optical Diffraction Tomography

Cortico-muscular connectivity is modulated by passive and active Lokomat-assisted Gait

Novel Design and Implementation of a Neuromuscular Controller on a Hip Exoskeleton for Partial Gait Assistance

lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Improving hand prosthesis control with advanced single-finger proportional decoding and robotic shared control

Brain-controlled spinal cord stimulation to restore mobility after spinal cord injury

Graph Chatbot

3D printed fiber-optic nanomechanical bioprobe

Exploring Novel Modalities for Optical Diffraction Tomography

Cortico-muscular connectivity is modulated by passive and active Lokomat-assisted Gait

Novel Design and Implementation of a Neuromuscular Controller on a Hip Exoskeleton for Partial Gait Assistance

lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Improving hand prosthesis control with advanced single-finger proportional decoding and robotic shared control

Brain-controlled spinal cord stimulation to restore mobility after spinal cord injury

Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase

Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase