Publication
The synthesis of the biological active undecapeptide substance P with the liquid-phase method (LPM) is described. The over-all-yield of the synthesis is high and the peptide shows full biological activity. The synthesis demonstrates that the modification of the liquid-phase synthesis, the cristallisation method, enables the preparation of peptides in short time with high yield and purity.
Ignacio Pagonabarraga Mora, Xiaoqi Zhang, Shan Chen
Eric Boillat, Alexandre Masserey, Bastian Meylan