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Organoid tissue engineering

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Matthias Lütolf, Nathalie Brandenberg, Yoji Tabata, Mikhail Nikolaev, Nikolche Gjorevski
2018

Abstract

The invention relates to methods for developing and maintaining organoids and the organoids produced thereby.

Official source

https://infoscience.epfl.ch/entities/publication/7d1ab6d3-a04d-460d-b2e4-1b0cfcab7adb

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Related concepts (6)

An organoid is a miniaturized and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural and biological complexity of that organ. They are derived from one or a few cells from a tissue, embryonic stem cells or induced pluripotent stem cells, which can self-organize in three-dimensional culture owing to their self-renewal and differentiation capacities. The technique for growing organoids has rapidly improved since the early 2010s, and The Scientist names it as one of the biggest scientific advancements of 2013.

Developing country

A developing country is a sovereign state with a less developed industrial base and a lower Human Development Index (HDI) relative to other countries. However, this definition is not universally agreed upon. There is also no clear agreement on which countries fit this category. The terms low and middle-income country (LMIC) and newly emerging economy (NEE) are often used interchangeably but refers only to the economy of the countries.

Small Island Developing States

Small Island Developing States (SIDS) are a group of developing countries that are small island countries and tend to share similar sustainable development challenges. These include small but growing populations, limited resources, remoteness, susceptibility to natural disasters, vulnerability to external shocks, excessive dependence on international trade, and fragile environments.

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