Improved spectral resolution in COSY proton NMR spectra of proteins via double quantum filtering
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As a simple approach to 3-dimensional NMR spectroscopy a novel type of expt. is proposed in which the dimension is reduced from 3 to 2 by synchronous incrementation of evolution period t, and the mixing time tm parameters: tm = Kt1. Because of the concerte ...
The resoln. in heteronuclear 2-dimensional NMR spectroscopy is affected by coherence transfer echoes. By introducing a delay between the transfer of coherence and the signal observation, the resoln. in the crucial w1 dimension can be enhanced. This procedu ...
A novel class of NMR expts., based on the systematic variation of 3 time variables, permits both the identification of exchange networks and the direct measurement of the corresponding rate consts. in soln. Linear combinations of cross sections taken from ...
The study of the diffusion of longitudinal scalar order in macromols. in isotropic soln. by 2-dimensional exchange spectroscopy provides addnl. insight into cross-relaxation pathways. [on SciFinder (R)] ...
An optimization procedure is described for NMR techniques that require signal averaging of expts. with a variable time delay ti, either for the suppression of artifacts or for the optimization of coherence transfer over a given frequency range. The procedu ...
In NMR spectroscopy in an isotropic phase, coherence can be transferred with a single rf pulse between 2 spins which possess no mutual scalar coupling. Such anomalous coherence processes are assocd. with multiexponential transverse relaxation that can aris ...
Chem. shifts and scalar coupling consts. were extd. by symmetry mapping of multiplets in 2-dimensional NMR spectra. The procedure relies on the fact that, in addn. to symmetry with respect to the centers of the multiplets, substructures embedded within the ...
In applications to systems with resolved scalar couplings, the 2-dimensional exchange expt. (NOESY: nuclear Overhauser effect spectroscopy) can provide greatly increased information if the flip angles of the 2 pulses that precede and follow the mixing inte ...
Cross-correlation between proton chem. shift anisotropy and proton-proton dipolar interactions is shown to be an important relaxation mechanism. Cross-correlation leads to a partial conversion of Zeeman order into longitudinal two-spin order. The build-up ...