Principles of an efficient new method for the removal of ammonia from animal cell cultures using hydrophobic membranes
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Bubble-free aeration is applied in animal cell culture processes for oxygenation to avoid shear stress and foaming assocd. with direct sparging into the culture. Oxygen mass transfer across PTFE-membranes was detd. in three different reactor systems that m ...
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Society of Environmental Toxicology and Chemistry Press2001
A review with many refs. Ammonia has been reported to be toxic and inhibitory for mammalian cell cultures for many years. Redn. of growth rates and maximal cell densities in batch cultures, changes in metabolic rates, perturbation of protein processing and ...
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