Formation and characterization of lipopeptide layers at interfaces for the molecular recognition of antibodies
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In a recent paper, a new class of synthetic lipids, which self-assemble to form monolayers on gold surfaces, was introduced. The addn. of a monolayer of phospholipids to these layers results in robust supported lipid bilayers designed to reconstitute trans ...
The structure of self-assembled monolayers of a long-chain perfluoro mercaptan was studied by using mol. dynamics simulations. The particular system studied (e.g., perfluorooctyl mercaptoethylamide) was chosen because it offers the possibility of generatin ...
In this work, the specific and nonspecific binding of proteins to planar surfaces was investigated. The surfaces were first modified by the spontaneous adsorption of a number of synthesized 1,2-diacyl-sn-glycero-3-phosphatidylcholine lipids with different ...
The controlled incorporation of polypeptides and proteins into micropatterened lipid mono- and bilayers on solid supports provide important understanding of the structural organization of membrane components and have potential applications in such fields a ...
A bilayer lipid membrane sensor comprises (1) a gold recording surface; (2) a 1st lipid layer which is an imperfect layer of a thiolipid comprising the 2 phospholipid mols. linked to each end of a disulfide group, each through an oxyethylene chain short en ...
The mol. self-organization and structural properties of peptide assemblies at different interfaces, using either amphipathic or hydrophobic polypeptide helixes, is described. The two peptides under investigation form stable monolayers on the water surface ...
The formation of supported lipid layers incorporating promastigote surface protease (PSP), a glycosylphosphatidylinositol-anchored protein, is investigated using surface plasmon resonance. Both hydrophilic and hydrophobic substrates are used for the format ...
The formation of supported lipid mono- and bilayers on a thiol-coated surface was monitored by utilising the acoustic Love waveguide device. The detection of the lipid layers was used as a model system for relating the phase response to the deposited mass ...
We demonstrate that the combined application of Langmuir-Blodgett and self-assembly techniques allows the fabrication of patterns with contrasting surface properties on gold substrates. The process is monitored using fluoroscence microscopy and surface pla ...