Bioanalytical reagent, method for production thereof, sensor platforms and detection methods based on use of said bioanalytical reagent

The invention relates to various embodiments of a bioanal. reagent with at least one vesicle, generated from a living cell, and at least one receptor for study of signal transduction. The invention further relates to methods for prodn. of said bioanal. reagent, application of a bioanal. detection technique based on this reagent, and use of this detection method and the bioanal. reagent. Examples include detection of the ligand binding capability of 5HT3A-receptors and the induction of ion channel activity of 5HT3A-receptors after the binding of a specific ligand. [on SciFinder (R)]