Effects of fibrin micromorphology on neurite growth from dorsal root ganglia cultured in three-dimensional fibrin gels
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The vast number of propagating solutions to the wave equation in multimode optical fibers represents a larger information capacity than provided by fiber bundles of the same diameter. Therefore, in the field of imaging, multimode fibers potentially allow t ...
Neurotrophic factors (NTFs) promote nerve regeneration and neuronal survival after peripheral nerve injury. However, drawbacks related with administration and bioactivity during long periods limit their therapeutic application. In this study, PLGA microsph ...
Peripheral nerve regeneration following injury occurs spontaneously, but many of the processes require metabolic energy. The mechanism of energy supply to axons has not previously been determined. In the central nervous system, monocarboxylate transporter ...
Regenerative peripheral nerve interfaces are particularly invasive implant devices. They rely on the growth of axons from transected nerve stumps through electrode-bearing structures in order to establish highly efficient communication channels with the ne ...
Peripheral nerve injury is a serious problem affecting significantly patients' life. Autografts are the "gold standard" used to repair the injury gap, however, only 50% of patients fully recover from the trauma. Artificial conduits are a valid alternative ...
We have fabricated a soft silicone structure to support the regeneration of a sciatic nerve. The device consists of 70 parallel (120 x 110 mu m(2)) channels through which axons extend and then reconnect to the muscles on the other side of the device. Throu ...
Dorsal root ganglia (DRG) neurons, located in the intervertebral foramina of the spinal column, can be used to create an in vitro system facilitating the study of nerve regeneration and myelination. The glial cells of the peripheral nervous system, Schwann ...
To what extent, how and when axons respond to injury in the highly interconnected grey matter is poorly understood. Here we use two-photon imaging and focused ion beam-scanning electron microscopy to explore, at synaptic resolution, the regrowth capacity o ...
Given a fiber bundle of GKM spaces, pi: M -> B, we analyze the structure of the equivariant K-ring of M as a module over the equivariant K-ring of B by translating the fiber bundle, pi, into a fiber bundle of GKM graphs and constructing, by combinatorial t ...
Let T be a torus and B a compact T-manifold. Goresky et al. show in [3] that if B is (what was subsequently called) a GKM manifold, then there exists a simple combinatorial description of the equivariant cohomology ring H-T*(B) as a subring of H-T*(B-T). I ...