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Publication
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Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
Lithiation of N-(2,2-diethoxyethyl)benzylamines I (R = Me, PhCH2) and reaction with electrophiles followed by acid-catalyzed cyclization leads to isoquinolines II (R1 = Me, MeO, CH2OH, MeS, Cl, Br, iodo) in 37-75% yield. [on SciFinder (R)]