A short and simple access to both enantiomers of epi-b-santalene and (Z)-epi-b-santalol
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Organometallic ruthenium(II) arene complexes containing the PTA ligand ([Ru(eta(6)-arene)Cl-2(PTA)], PTA = 1,3,5-triaza-7-phosphatricyclo-[3.3.1.1] decane, termed RAPTA) show pharmacologically relevant antitumour properties in vitro. Two new enantiomeric p ...
Both enantiomers of an optically active trialkynyl(phenyl)methane (the key building blocks in the construction of a stable expanded cubane) have been prepd. The strategy involved the resoln. of a racemic intermediate by means of HPLC on a chiral stationary ...
Enantioselective catalytic methods allowing the addition of both a nucleophile and an electrophile onto diazo compounds give a fast access into important building blocks. Herein, we report the highly enantioselective oxyalkynylation of diazo compounds usin ...
The Bingel addn. of a trimalonate derived from a chiral, cyclotriveratrylene (CTV)-based tripodal tether to C60 was reinvestigated. The present use of enantiomerically pure (P)- and (M)-configured CTV units in the tether allowed the isolation of a total of ...
This thesis deals with the supramolecular organization of chiral aminoacids and dipeptides on metal surfaces. The emergence of homochirality in biomolecular systems is one of the most intriguing open questions of Nature. The self-assembly and amplification ...
By addn. of an enantiomerically pure nitrile oxide to C70, four chiral isoxazolo[70]fullerene isomers were prepd. and isolated in pure state: two constitutional isomers resulting from addn. to one of the bonds radiating from the polar pentagons, and a cons ...
(1R)-Normetanephrine is the natural stereoisomeric substrate for sulfotransferase 1A3 (SULT1A3)-catalyzed sulfonation. Nothing appears known on the enantioselectivity of the reaction despite its potential significance in the metabolism of adrenergic amines ...
Mix and go. The quinidine-amide (1)-catalyzed [2+2] cycloaddition between N-sulfonylimines (2) and alkyl 2,3-butadienoate (3) afforded the (R)-azetidines 4 in excellent yields and enantioselectivities. The (S)-enantiomer was obtained when a quinine-amide c ...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary centers with high enantioselectivity is reported. The required starting materials were readily accessed in racemic form through the alpha-alkynylation of ket ...
The enantiomerically pure pinene-bipyridine-based receptor, (-) or (+) L-, diastereoselectively self-assembles in dry acetonitrile in the presence of Ln(III) ions (Ln = La, Pr, Nd, Sm, Eu, Gd, and Tb) to give a C-3-symmetrical, pyramidal architecture with ...