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A simulation tool for building and lighting design considering ipRGC-influenced light responses

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Reduced order models for coupled systems

Niccolo' Discacciati

Efficient numerical simulations of coupled multi-component systems can be particularly challenging. This is mostly due to the complexity of their solutions, as mutual interactions may cause emergent behaviors, including synchronization and instabilities. V ...

EPFL2023

Comparison of questionnaire items for discomfort glare studies in daylit spaces

Marilyne Andersen, Jan Wienold, Caroline Karmann, Sneha Jain, Clotilde Marie A Pierson, Geraldine Cai Ting Quek

When studying discomfort glare, researchers tend to rely on a single questionnaire item to obtain user evaluations. It is unclear whether the choice of questionnaire item affects the distribution of user responses and leads to inconsistencies between studi ...

2023

Closed form approximation methods for portfolio valuation and risk management

Lotfi Boudabsa

In this thesis we present three closed form approximation methods for portfolio valuation and risk management. The first chapter is titled ``Kernel methods for portfolio valuation and risk management'', and is a joint work with Damir Filipovi'c (SFI and ...

EPFL2023

Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

Jean-Louis Scartezzini, Mirjam Münch, Marta Benedetti, Lenka Maierova

Improving indoor lighting conditions at the workplace has the potential to support proper circadian entrainment of hormonal rhythms, sleep, and well-being. We tested the effects of optimized dynamic daylight and electric lighting on circadian phase of mela ...

Nature Research2022

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

ELSEVIER2022

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

Howard Riezman, Jonathan Paz Montoya

Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in ...

PUBLIC LIBRARY SCIENCE2022

Validation of spectral simulation tools in the context of ipRGC-influenced light responses of building occupants

Marilyne Andersen, Clotilde Marie A Pierson

With the growing awareness about ipRGC-influenced light (IIL) responses, design applications related to these responses are flourishing. To compare design options and optimize lighting conditions for building occupants, lighting simulations are typically u ...

2023

Theory and application of a data-driven approach to compressive spectrometry in the assessment of neurophotic stimulation

Forrest Simon Webler

Recent advances in biology and neuroscience have elucidated pathways in which visible light initiates a signaling process, via the eye, responsible for activating direct and indirect biological responses. While the full impact of unnatural light patterns o ...

EPFL2022

Illiquidity and Higher Cumulants

Semyon Malamud, Alberto Mokak Teguia

We characterize the unique equilibrium in an economy populated by strategic CARA investors who trade multiple risky assets with arbitrarily distributed payoffs. We use our explicit solution to study the joint behavior of illiquidity of option contracts. Op ...

OXFORD UNIV PRESS INC2022

Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver

Felix Naef, Cédric Gobet, Benjamin Dieter Weger, Clémence Yumie Syloun Hurni

In eukaryotes, RNA is synthesised in the nucleus, spliced, and exported to the cytoplasm where it is translated and finally degraded. Any of these steps could be subject to temporal regulation during the circadian cycle, resulting in daily fluctuations of ...

PUBLIC LIBRARY SCIENCE2022

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Theory and application of a data-driven approach to compressive spectrometry in the assessment of neurophotic stimulation

Forrest Simon Webler

EPFL2022

Illiquidity and Higher Cumulants

Semyon Malamud, Alberto Mokak Teguia

OXFORD UNIV PRESS INC2022

Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver

Felix Naef, Cédric Gobet, Benjamin Dieter Weger, Clémence Yumie Syloun Hurni

PUBLIC LIBRARY SCIENCE2022

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

ELSEVIER2022